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2015 | 09 | 2 |

Tytuł artykułu

The presence of interfering antibodies in selected control sera on the example of a set for determination of tPSA

Treść / Zawartość

Języki publikacji

EN

Abstrakty

EN
The human sera often contain substances which interfere in the course of immunochemical reactions. It is essential for the control sera used to determine concentrations of antigen of the prostate not to contain such ingredients. The aim of this study was to test the control sera, three producers, containing low (N) and high (P) concentrations of prostate antigen (tPSA). As a factor blocking the interfering actions, the TRU Bloc Meridian Life Science, Inc. reagent was used which contains antibodies against mouse protein and rheumatoid factor. The sera with a low concentration of tPSA demonstrated the presence of interfering substances.

Wydawca

-

Rocznik

Tom

09

Numer

2

Opis fizyczny

p.55-57,ref.

Twórcy

  • Department and Chair of General Biology, Medical Faculty of Medicine and Medical-Dental Division, Medical University of Silesia in Katowice, Katowice, Poland
  • Department and Chair of General Biology, Medical Faculty of Medicine and Medical-Dental Division, Medical University of Silesia in Katowice, Katowice, Poland
  • Department and Chair of General Biology, Medical Faculty of Medicine and Medical-Dental Division, Medical University of Silesia in Katowice, Katowice, Poland
  • Department and Chair of General Biology, Medical Faculty of Medicine and Medical-Dental Division, Medical University of Silesia in Katowice, Katowice, Poland
autor
  • Department and Chair of General Biology, Medical Faculty of Medicine and Medical-Dental Division, Medical University of Silesia in Katowice, Katowice, Poland
autor
  • Department of Nursing, Higher School of Strategic Planning in Dabrowa Gornicza, Dabrowa Gornicza, Poland

Bibliografia

  • 1. Bonetti A ., M onica C ., Bonaguri C ., Gnocchi C ., Russo A ., B attistelli L ., Musiari L ., P astori P., Novarini A . (2008), Interference by heterophilic antibodies in immunoassay: wrong increase of myoglobin values. Acta Biomed 79: 140-143.
  • 2. Instrukcja firmy STAMAR do zestawu do oznaczania antygenu PSA nr kat.91.206.
  • 3. Instrukcja producenta tPSA DiaMetra 06034 Foligno (PG)- Italy.
  • 4. Instrukcja firmy Meridian Life Science,Inc. do TRU Block Active Blocker against Heterofilic Antibodies and Rheumatoid Factor.
  • 5. Kricka L.J. (1999), Human anti-animal antibody interferences in immunological assays. Clin. Chem. 45(7): 942-956.
  • 6. Park S., Wians F., Cadeddu J. (2006), Spurious prostate - specific antygen (PSA) recurrence after radical prostatectomy: Interference by human antimouse heterophile antibodies. International Journal of Urology 14: 251-253.
  • 7. Stenman U.H. (2001), Immunoassay standaryzation: it is possible, who is responsible, who is capable. ClinChem. 47:815-820.
  • 8. Sztefko K. (2002), Wykłady monograficzne z diagnostyki laboratoryjnej część 1. Wydawnictwo Uniwersytetu Jagiellońskiego, Kraków.
  • 9. Sztefko K. (2011), Problemy standaryzacji i kalibracji metod immunochemicznych. Dian.Lab. 47:7-15.
  • 10. Turpelnen U., Lehtovirta P., Alfthan H., Stenman U. (1990), Interference by Human Anti- Mouse Antibodies in Ca 125 Assay after immunoscintigraphy: Anti- Idiotypic Antibodies Not Neutralized by Mouse IgG but Removed by Chromatography. ClinChem. 36:1333-1338.
  • 11. Zhu L., Leinonen J., Zhang W., Finne P., Stenman U. (2003), Dual- Label Immunoassay of Prostate- specific Antygen (PSA)- α1- Antichymotrypsin Comlex Together with Free or Total PSA. Clin. Chem. 49:1; 97-103.

Identyfikator YADDA

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