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2018 | 74 | 12 |

Tytuł artykułu

Myonecrosis in a horse after an intramuscular injection of menbutone

Warianty tytułu

Języki publikacji

EN

Abstrakty

EN
Myonecrosis after intramuscular injections is not common, but may be life-threatening. This case report describes myonecrosis following an accidental intramuscular injection of menbutone. A three-year-old bay French Trotter stallion with a history of weak appetite and colic lasting ten days was treated by a field veterinarian. During the course of treatment, he was given paraffin oil and antihelminthics orally, antispasmodics, analgesics, steroids and antibiotics intravenously, as well as choleretics intramuscularly. The horse was apathetic and weak with a “tucked up” abdomen and had grade 2 ataxia, according to Mayhew’s grading system. The patient had a swollen neck on both sides and a swelling of the right front limb and the carpal area of the left front limb. The neck edema was painful and warm. The neck area was prepared and punctured; a malodorous fluid was obtained for cytology. In the material obtained, there were anaerobic rod bacteria diagnosed as Clostridium spp. Surgical fenestration and debridement were performed. The wounds were cleaned every day. The horse was given antibiotics, nonsteroidal antinflammatory drugs, fluids and gastroprotectives. After five weeks of intensive care, the condition of the horse stabilized, and significant improvement was observed. Myonecrosis may be a rare life-threatening complication following intramuscular injections or wound contamination. To the authors’ best knowledge, this is the first published report of myonecrosis after menbutone injections in the horse.

Wydawca

-

Rocznik

Tom

74

Numer

12

Opis fizyczny

p.795-798,fig.,ref.

Twórcy

  • Department of Internal Medicine and Clinic of Diseases of Horses, Dogs and Cats, Faculty of Veterinary Medicine, Wroclaw University of Environmental and Life Sciences, Pl.Grunwaldzki 47, 50-366 Wroclaw, Poland
autor
  • Department of Internal Medicine and Clinic of Diseases of Horses, Dogs and Cats, Faculty of Veterinary Medicine, Wroclaw University of Environmental and Life Sciences, Pl.Grunwaldzki 47, 50-366 Wroclaw, Poland
autor
  • Department of Internal Medicine and Clinic of Diseases of Horses, Dogs and Cats, Faculty of Veterinary Medicine, Wroclaw University of Environmental and Life Sciences, Pl.Grunwaldzki 47, 50-366 Wroclaw, Poland
autor
  • Department of Internal Medicine and Clinic of Diseases of Horses, Dogs and Cats, Faculty of Veterinary Medicine, Wroclaw University of Environmental and Life Sciences, Pl.Grunwaldzki 47, 50-366 Wroclaw, Poland
autor
  • Department of Internal Medicine and Clinic of Diseases of Horses, Dogs and Cats, Faculty of Veterinary Medicine, Wroclaw University of Environmental and Life Sciences, Pl.Grunwaldzki 47, 50-366 Wroclaw, Poland
  • Department of Internal Medicine and Clinic of Diseases of Horses, Dogs and Cats, Faculty of Veterinary Medicine, Wroclaw University of Environmental and Life Sciences, Pl.Grunwaldzki 47, 50-366 Wroclaw, Poland

Bibliografia

  • Adam E. N., Southwood L. L.: Surgical and traumatic wound infections, cellulitis, and myositis in horses. Vet. Clin. North Am. Equine Pract. 2006, 22, 335-361.
  • Anderson F. L., Secombe C. J., Lester G. D.: Clostridial myonecrosis, haemolytic anaemia, hepatopathy, osteitis and transient hypertrophic cardiomyopathy after intramuscular injection in a Thoroughbred gelding. Aust. Vet. J. 2013, 91, 204-208.
  • Bakker D. J.: Clostridial myonecrosis (gas gangrene). Undersea Hyperb. Med. 2012, 39, 731-737.
  • Breuhaus B. A., Brown C. M., Scott E. A., Ainsworth D. M., Taylor R. F.: Clostridial muscle infections following intramuscular injections in the horse. J. Eqine Vet. Sci. 1983, 3, 42-46.
  • Brook I.: Microbiology and management of soft tissue and muscle infections. Int. J. Surg. 2008, 6, 328-338.
  • Brown C. M., Kaneene J. B., Walker R. D.: Intramuscular injection techniques and the development of clostridial myositis or cellulitis in horses. J. Am. Vet. Med. Assoc. 1988, 193, 668-670.
  • Coloe P. J., Ireland L., Vaudrey J. C.: Clostridium fallax as a cause of gas-oedema disease in a horse. J. Comp. Pathol. 1983, 93, 597-601.
  • Crum-Cianflone N. F.: Bacterial, fungal, parasitic, and viral myositis. Clin. Microbiol. Rev. 2008, 21, 473-494.
  • EMEA: Committee for veterinary medicinal products. Menbutone. Summary report. The European Agency for the Evaluation of Medicinal Products Veterinary Medicine Evaluation Unit 1996, EMEA/MRL/106/196-FINAL.
  • Farias L. D., Azevedo Mda S., Trost M. E., De La Corte F. D., Irigoyen L. F., de Vargas A. C.: Acute myonecrosis in horse caused by Clostridium novyi type A. Braz. J. Microbiol. 2014, 45, 221-224.
  • Hagemoser W. A., Hoffman L. J., Lundvall R. L.: Clostridium chauvoei infection in a horse. J. Am. Vet. Med. Assoc. 1980, 176, 631-633.
  • Jeanes L. V., Magdesian K. G., Madigan J. E., Meagher D.: Clostridial Myositis in Horses. Comp. Cont. Edu. Pract. Vet. 2001, 23, 577-587.
  • MacKay R. J., Carlson G. P., Hirsh D. C.: Clostridium perfringens Associated with a Focal Abscess in a Horse. J. Am. Vet. Med. Assoc. 1979, 175, 71-72.
  • May K. A., Cheramie H. S., Howard R. D., Duesterdieck K., Moll H. D., Pleasant R. S., Pyle R. L.: Purulent pericarditis as a sequela to clostridial myositis in a horse. Equine Vet. J. 2002, 34, 636-640.
  • Murphy D. B.: Clostridium chauvoei as the cause of malignant edema in a horse. Vet. Med. Small Anim. Clin. 1980, 75, 1152-1154.
  • Nation P. N., Frelier P. F., Schoonderwoerd M.: Clostridial Myositis Following Ivermectin Administration. Can. Vet. J. 1983, 24, 295.
  • Peek S. F., Semard S. D.: Clostridial myonecrosis in horses. Equine Vet. Edu. 2002, 14, 163-168.
  • Peek S. F., Semrad S. D., Perkins G. A.: Clostridial myonecrosis in horses (37 cases 1985-2000). Equine Vet. J. 2003, 35, 86-92.
  • Rebhun W. C., Shin S. J., King J. M., Baum K. H., Patten V.: Malignant edema in horses. J. Am. Vet. Med. Assoc. 1985, 187, 732-736.
  • Reef V. B.: Clostridium perfringens cellulitis and immune-mediated hemolytic anemia in a horse. J. Am. Vet. Med. Assoc. 1983, 182, 251-254.
  • Stevens D. L., Maier K. A., Laine B. M., Mitten J. E.: Comparison of clindamycin, rifampin, tetracycline, metronidazole, and penicillin for efficacy in prevention of experimental gas gangrene due to Clostridium perfringens. J. Infect. Dis. 1987, 155, 220-228.
  • Valberg S. J., McKinnon A. O.: Clostridial Cellulitis in the Horse: A Report of Five Cases. Can. Vet. J. 1984, 25, 67-71.
  • Vengust M., Arroyo L. G., Weese J. S., Baird J. D.: Preliminary evidence for dormant clostridial spores in equine skeletal muscle. Equine Vet. J. 2003, 35, 514-516.
  • Westman C. W., Traub J. L., Schroeder W. G.: Clostridial infection in a horse. J. Am. Vet. Med. Assoc. 1979, 174, 725-726.

Typ dokumentu

Bibliografia

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