The influence of non-specific anti-pruritus treatment with cyclosporine A on transepidermal water loss (TEWL) in natural atopic dermatitis in dogs

• Autorzy: Zajac M. , Szczepanik M. , Wilkolek P. , Adamek L. , Pomorski Z.
• Języki publikacji: EN

Abstrakty

EN

Atopic dermatitis is a common allergic skin disease in dogs. Monitoring the progress of treatment and the assessment of the severity of disease symptoms are crucial elements of the treatment procedure. One of the common means of assessing the severity of the clinical signs of the disease is the CADESI 03. Research studies have pointed to a possibility of assessing the severity of skin lesions by means of measuring biophysical skin parameters such as TEWL, skin hydration and erythema intensity. The aim of the study was the assessment of changes in TEWL and CADESI values measured in ten different body regions during non-specific anti-pruritus treatment. The examination was performed on ten dogs with atopic dermatitis (age from 2.5 years to 7 years, mean age 3.8 years). The measurements were performed in the following body regions: the lumbar region, the right axillary fossa, the right inguinal region, the ventral abdominal region, the right lateral thorax region, the internal surface of the auricle, interdigital region of the right forelimb, cheek, bridge of nose and the lateral site of antebrachum. A statistically significant decrease in CADESI values was reported starting from the second week of treatment. In the case of the mean TEWL values, a fall was observed after one week of treatment in the ventral abdominal region and the interdigital region, after two weeks of treatment in the axillary fossa and the inguinal region, and after three weeks in the cheek and the lateral thorax region. There was no statistically significant decrease in TEWL values in the course of treatment in four other regions.

• Wydawca: -
• Czasopismo: Polish Journal of Veterinary Sciences
• Rocznik: 2015
• Tom: 18
• Numer: 2
• Opis fizyczny: p.415-424,fig.,ref.

Twórcy

autor

Zajac M.

• Private veterinary practice Bafir in Czeladz, Szpitalna 9A, Czeladz, Poland

autor

Szczepanik M.

• Subdepartment of Clinical Diagnostics and Veterinary Dermatology, University of Life Science, Gleboka 30, 20-612 Lublin, Poland

autor

Wilkolek P.

• Subdepartment of Clinical Diagnostics and Veterinary Dermatology, University of Life Science, Gleboka 30, 20-612 Lublin, Poland

autor

Adamek L.

• Subdepartment of Clinical Diagnostics and Veterinary Dermatology, University of Life Science, Gleboka 30, 20-612 Lublin, Poland

autor

Pomorski Z.

• Subdepartment of Clinical Diagnostics and Veterinary Dermatology, University of Life Science, Gleboka 30, 20-612 Lublin, Poland

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Identyfikatory

DOI

10.1515/pjvs-2015-0053