Chemical constituents of ethanol extract of leaves and molluscicidal activity of crude extracts from Vitex trifolia Linn.

• Autorzy: Jangwan J.S. , Aquino R. P. , Mencherini T. , Picerno P. , Singh R.

Warianty tytułu

PL

Składniki chemiczne etanolowego wyciągu z liści i działanie przeciwślimakowe nieoczyszczonego wyciągu z Vitex trifolia Linn.

• Języki publikacji: EN

Abstrakty

EN

β-sitosterol and two triterpenoids: ursolic acid acetate and platanic acid have been isolated from ethanolic extract of Vitex trifola leaves. β-sitosterol was previously isolated from the leaves, stem and seeds of Vitex trifolia. Ursolic acid acetate has been isolated for the first time in this plant species. Platanic acid has been reported for the first time in Vitex trifolia and even in the family of this plant: Verbenaceae. These compounds were characterized using spectroscopic methods including 1D-1HNMR, 13CNMR, ESIMS and 2D-NMR (HSQC, HMBC, COSY) experiments and confirmed by comparison of their NMR data with those from the literature. A preliminary molluscicidal test for ethanol, chloroform and n-hexane extracts of leaves of Vitex trifolia against Biomphalaria alexandrina adult snails showed that ethanol extract of leaves with LC50 value 26.42 mg/l (27.92 mg/l – 24.99 mg/l) was more effective than n-hexane extract with LC50 value 35.48 mg/l (43.81 mg/l – 28.72mg/l) and chloroform extract with LC50 value 46.77 mg/l (53.59 mg/l – 43.81 mg/l) after 24 h exposure.

PL

Z etanolowego wyciągu z liści Vitex trifola wyizolowano β-sitosterol i dwa triterpenoidy: octan kwasu ursolowego i kwas platanowy. Poprzednio z liści, łodyg i nasion Vitex trifola był wyizolowant β-sitosterol. Octan kwasu ursolowego został wyizolowany po raz pierwszy z rośliny tego gatunku. Występowanie kwasu platanowego w Vitex trifolia oraz w rodzinie Verbenaceae zostało opisane po raz pierwszy. Składniki te scharakteryzowano, używając metod spektroskopowych, stosując badania 1D-1HNMR, 13CNMR, ESIMS and 2D-NMR (HSQC, HMBC, COSY) oraz potwierdzono porównaniem ich danych NMR z danymi literaturowymi. Wstępny test działania przeciwślimakowego wyciągów etanolowego, chloroformowego i n-heksanowego z liści Vitex trifolia przeciw dorosłym ślimakom Biomphalaria

Słowa kluczowe

EN

chemical constituent; ethanol extract; leaf; molluscicidal activity; crude extract; Vitex trifolia; Verbenaceae; beta-sitosterol; ursolic acid acetate

• Wydawca: -
• Czasopismo: Herba Polonica
• Rocznik: 2013
• Tom: 59
• Numer: 4
• Opis fizyczny: p.19-32,fig.,ref.

Twórcy

autor

Jangwan J.S.

• Department of Chemistry, H.N.B.Garhwal Central University SRT Campus, Badshahi thaul Tehri Garhwal (U.K.), India

autor

Aquino R. P.

• Department of Pharmaceutical and Biomedical Sciences, University of Salerno, Italy

autor

Mencherini T.

• Department of Pharmaceutical and Biomedical Sciences, University of Salerno, Italy

autor

Picerno P.

• Department of Pharmaceutical and Biomedical Sciences, University of Salerno, Italy

autor

Singh R.

• Department of Chemistry, H.N.B.Garhwal Central University SRT Campus, Badshahi thaul Tehri Garhwal (U.K.), India

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Identyfikatory

DOI

10.2478/hepo-2013-0021