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2016 | 52 |

Tytuł artykułu

Association of ACE DD genotype with Hypertension among the tribal populations of South India

Treść / Zawartość

Warianty tytułu

Języki publikacji

EN

Abstrakty

EN
The Renin-Angiotensin System (RAS) is an important regulator of the blood pressure(BP). The level of the vasoactive peptide Angiotensin-II, is mainly determined by the RAS enzyme, angiotensin converting enzyme-1 (ACE-1). Polymorphisms in ACE gene is reported to be associated with hypertension in various populations worldwide. We investigated the association of ACE I/D polymorphisms with hypertension among the tribal populations of South India. Samples were collected from hypertensive patients (n = 33) and healthy controls (n = 37). Genotyping was performed using Polymerase chain reaction (PCR) with allele specific primers. The DD genotype is significantly observed among the cases (OR = 1.0) . Specifically, the DD genotype is more evident among the females (OR = 0 .705) than males (OR = 1.22) and is analysed to be associated with hypertension among the tribal populations of South India.

Wydawca

-

Rocznik

Tom

52

Opis fizyczny

p.1-8,fig.,ref.

Twórcy

  • Research Scholar, PG and Research Department of Zoology, Periyar E.V.R College, Tiruchirappalli - 620023, Tamilnadu, India
  • Research Scholar, PG and Research Department of Zoology, Periyar E.V.R College, Tiruchirappalli - 620023, Tamilnadu, India
autor
  • Research Scholar, PG and Research Department of Zoology, Periyar E.V.R College, Tiruchirappalli - 620023, Tamilnadu, India
autor
  • Research Scholar, PG and Research Department of Zoology, Periyar E.V.R College, Tiruchirappalli - 620023, Tamilnadu, India

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Bibliografia

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