PL EN


Preferencje help
Widoczny [Schowaj] Abstrakt
Liczba wyników
2014 | 09 |

Tytuł artykułu

Toxicity study of Achyranthus aspera

Treść / Zawartość

Warianty tytułu

Języki publikacji

EN

Abstrakty

EN
The objectives of present work focuses to check the acute and sub acute toxicity studies for the Achyranthes aspera L methanol extract as per OECD guideline in Swiss mice. The dose of 100, 200, 250 gm/kg body weight methanol extract by administering drug intraperitoneally and recorded the growth, body weight, organ weight, general symptoms, morphological and physiological behavior, mortality. These parameters on various organs system in mice were studied. It was considered necessary to assess its potential health hazard in man and to find the safe and effective dose. The observations of changes in body weight, food and water intake as well as cage side observations were reported. There was no abnormality observed in all groups. The whole plant powder methanol extract of Achyranthes Aspera L were found to be nontoxic.

Słowa kluczowe

Wydawca

-

Rocznik

Tom

09

Opis fizyczny

p.85-96,fig.,ref.

Twórcy

autor
  • Department of Biotechnology, Gulbarga University, Gulbarga 585106, Karnataka, India
autor
  • Department of Biotechnology, Gulbarga University, Gulbarga 585106, Karnataka, India

Bibliografia

  • [1] K. Olejniczak, P. Günzel, R. Bass, Drug Information Journal 35(2) (2001) 321-336.
  • [2] Gokhale A. B., Damre A. S., Kulkarni K. R., Saraf M. N., Phytomedicine 9(5) (2002) 433-37.
  • [3] A. N. Ukwuani, M. G. Abubakar, S. W. Hassan, B. M. Agaie, International Journal of Pharmaceutical Science and Drug Research 4 (2012) 245-249.
  • [4] P. Suresh Kumar, S. Sucheta, V. Sudarshana Deepa, P. Selvamani, S. Latha, African Journal of Biotechnology 7(12) (2008) 1826-1828.
  • [5] Khan A. V., Alam M. M., Hamdard Medicus 52(1) (2003) 44-47.
  • [6] Khan A. V., Khan A. A., Journal of Natural Remedies 4(1) (2004) 73-76.
  • [7] Nath D., Sethi N., Srivastava S., Jain A. K., Fitoterapia 68(3) (1997) 223-225.
  • [8] Pakrashi A., Bhattacharya N., Indian Journal of Experimental Biology 15(10) (1977) 856-85.
  • [9] S. K. Uniyal, K. N. Singh, P. Jamwal, B. Lal, J. Ethnobiol 2 (2006) 1-14.
  • [10] Pakrashi A., Mookerji N., Basak B., Journal of Reproduction and Fertility 43(1) (1975) 127-129.
  • [11] Pingale Shirish S., Acute Pharmacologyonline Newsletter 3 (2008) 80-84.
  • [12] M. B. Rajeh, Y. P. Kwan, Z. Zakaria, L. Y. Latha, S. L. Jothy, S. Sasidharan, Pharmacognosy Research 4 (2012) 170-177.
  • [13] National Research Council (NRC), “Toxicity testing for assessing environmental agents,” Interim Report, National Academies Press, Washington, DC, USA, 2006.
  • [14] C. D. Klaassen, Casarett, Doull‟s Toxicology: The Basic Science of Poisons, McGraw- Hill Press, New York, NY, USA, 2001.
  • [15] B. Michael, B. Yano, R. S. Sellers, Toxicologic pathology 35(5) (2007) 742–750.
  • [16] Vetrichelvan T., Jegadeesan, Phytotherapy Research 17(1) (2003)77-79.
  • [17] D. Jaya Kumar, S. Jhancy Mary, R. Jaya Santhi, Indian Journal of Science and Technology 3(7) (2010) 720-723.

Typ dokumentu

Bibliografia

Identyfikatory

Identyfikator YADDA

bwmeta1.element.agro-b9af9320-ee2e-4324-8c70-5b055258382a
JavaScript jest wyłączony w Twojej przeglądarce internetowej. Włącz go, a następnie odśwież stronę, aby móc w pełni z niej korzystać.