Cellulase inhibits Burkholderia cepacia biofilms on diverse prosthetic materials

• Autorzy: Rajasekharan S.K. , Ramesh S.
• Języki publikacji: EN

Abstrakty

EN

Burkholderia cepacia is an opportunistic pathogen causing infections in patients with cystic fibrosis. Patients with implanted devices are prone to B. cepacia infections due to its ability to grow as biofilms. Knowing the importance of polysaccharides in a biofilm, enzymes that degrade them were targeted as a possible candidate for antibiofilm agents. In this study, the antibiofilm potential of cellulase against B. cepacia biofilms formed on various prosthetic materials was tested. Cellulase exhibited significant antibiofilm activity against B. cepacia without having much action on its growth, thus ruling out the chance of selection pressure and subsequent development resistance.

Słowa kluczowe

EN

cellulase; Burkholderia cepacia; biofilm; prosthetic material; pathogenesis; cystic fibrosis; chronic granulomatous disease

• Wydawca: -
• Czasopismo: Polish Journal of Microbiology
• Rocznik: 2013
• Tom: 62
• Numer: 3
• Opis fizyczny: p.327-330,fig.,ref.

Twórcy

autor

Rajasekharan S.K.

• Department of Microbiology, PRIST University, !anjavur, Tamil Nadu, India

autor

Ramesh S.

• Department of Microbiology, PRIST University, !anjavur, Tamil Nadu, India

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