Polymorphism of the PrP prion protein gene in Polish Merino and old-type Polish Merino from Brylewo flock

• Autorzy: Niznikowski R. , Oprzadek A. , Czub G. , Swiatek M. , Kubasik D. , Brzoza P. , Glowacz K. , Slezak M.
• Języki publikacji: EN

Abstrakty

EN

The study was conducted on Polish Merino (143 ♀ and 39 ♂ ) and old-type Polish Merino sheep (176♀ and 61♂ ) in Brylewo flock (Wielkopolskie Province). The examined sheep were at the age of one year. Prion protein (PrP) genotype was determined in all animals. In both breeds four alleles (ARR, ARQ, AHQ, VRQ) were found. Highly significant effect of breed and insignificant impact of gender within breed was observed in regard to the frequency of occurrence of alleles and genotypes susceptible to classical scrapie in the sheep. Eight different PrP genotypes in Polish Merino and nine genotypes in old-type Polish Merino were identified. Ven high frequency of ARR/ARR genotype in old-type Polish Merino and high frequency of ARR/ARQ genotype in Polish Merino were found, with relatively significant frequency of occurrence of the genotypes containing VRQ allele. In old-type Polish Merino, three animals (of both genders) had VRQ/VRQ genotype. Breeding work involving elimination of animals encoding valine at codon 136, and introduction of rams with ARR allele to the population increased the frequency of occurrence of ARR/ARR genoty pe and ARR allele in the population of old-type Polish Merino. To improve-the distribution of the genotypes genetically resistant to scrapie in the flock of Polish Merino only rams with ARR/ARR genotype were left. This guarantees an increase in the frequency of occurrence of genotypes genetically resistant to scrapie in the offspring.

• Wydawca: -
• Czasopismo: Bulletin of the Veterinary Institute in Puławy
• Rocznik: 2015
• Tom: 59
• Numer: 2
• Opis fizyczny: p.321-326,ref.

Twórcy

autor

Niznikowski R.

• Division of Sheep and Goat Breeding, Faculty of Animal Science, Warsaw University of Life Sciences, 02-786 Warsaw, Poland

autor

Oprzadek A.

• The Agricultural Property Agency, 00-215 Warsaw, Poland

autor

Czub G.

• Division of Sheep and Goat Breeding, Faculty of Animal Science, Warsaw University of Life Sciences, 02-786 Warsaw, Poland

autor

Swiatek M.

• Division of Sheep and Goat Breeding, Faculty of Animal Science, Warsaw University of Life Sciences, 02-786 Warsaw, Poland

autor

Kubasik D.

• Breeding Center „GARZYN”, 64-120 Krzemieniewo, Poland

autor

Brzoza P.

• Breeding Center „GARZYN”, 64-120 Krzemieniewo, Poland

autor

Glowacz K.

• Division of Sheep and Goat Breeding, Faculty of Animal Science, Warsaw University of Life Sciences, 02-786 Warsaw, Poland

autor

Slezak M.

• Division of Sheep and Goat Breeding, Faculty of Animal Science, Warsaw University of Life Sciences, 02-786 Warsaw, Poland

Bibliografia

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Identyfikatory

DOI

10.1515/bvip-2015-0047