Recombinant MAG1 protein of Toxoplasma gondii as a diagnostic antigen

• Autorzy: Gatkowska J.M. , Dziadek B. , Dziadek J. , Dzitko K. , Dlugonska H.
• Języki publikacji: EN

Abstrakty

EN

The aim of this study was to evaluate the potential diagnostic usefulness of the full-length recombinant Toxoplasma gondii MAG1 protein by determining the levels of specific IgM and IgG antibodies in mouse and human sera obtained from individuals with acute and chronic toxoplasmosis. The obtained results revealed that IgG antibodies against MAG1 are a sensitive and specific marker of T. gondii infection since the protein was recognized by both mouse and human sera, 100% and 94.3%, respectively, rendering the full-length rMAG1 a prospective alternative for the polyvalent native antigen (TLA).

• Wydawca: -
• Czasopismo: Polish Journal of Microbiology
• Rocznik: 2015
• Tom: 64
• Numer: 1
• Opis fizyczny: p.55-59,fig.,ref.

Twórcy

autor

Gatkowska J.M.

• Department of Immunoparasitology, Faculty of Biology and Environmental Protection, University of Lodz, Lodz, Poland

autor

Dziadek B.

• Department of Immunoparasitology, Faculty of Biology and Environmental Protection, University of Lodz, Lodz, Poland

autor

Dziadek J.

• Institute of Medical Biology, Polish Academy of Sciences, Lodz, Poland

autor

Dzitko K.

• Department of Immunoparasitology, Faculty of Biology and Environmental Protection, University of Lodz, Lodz, Poland

autor

Dlugonska H.

• Department of Immunoparasitology, Faculty of Biology and Environmental Protection, University of Lodz, Lodz, Poland

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