Concentration of porphyrins in rat liver and kidneys repeated administration of hexabromobenzene and tetrabromobisphenol-A

• Autorzy: Frydrych B , Szymanska J.A. , Swiderska-Comer A.
• Języki publikacji: EN

Abstrakty

EN

The aim of this study was to complete research on the porphyrogenic effect of hexabrombenzene (HBB) and tetrabromobisphenol-A (TBBP-A). Experiments were performed on female Wistar rats. The examined compounds were administered in sunflower oil intragastrically in 3 doses. The determination of porphyrins in tissues was carried out by means of high-performance liquid chromatography. Repeated HBB administration caused a 3-8 times increase of total concentration of high carboxylated porphyrins (octa- and heptacarboxyporphyrins). The concentrations of these porphyrins were significantly lower in the liver of rats exposed to tbbp-a. However, in the kidneys significant alterations in porphyrins concentrations concerned only HBB.

Słowa kluczowe

EN

concentration; tetrabromobisphenol-A; kidney; liver; rat; high performance liquid chromatography; hexabromobenzene; porphyrin

• Wydawca: -
• Czasopismo: Polish Journal of Environmental Studies
• Rocznik: 2006
• Tom: 15
• Numer: 4
• Opis fizyczny: p.543-548,fig.,ref.

Twórcy

autor

Frydrych B

• Medical University of Lodz, Lodz, Poland

autor

Szymanska J.A.

autor

Swiderska-Comer A.

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