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1997 | 44 | 1 |

Tytuł artykułu

The activities and subcellular localization of cathepsin B and cysteine proteinase inhibitors in human ovarian carcinoma

Warianty tytułu

Języki publikacji

EN

Abstrakty

EN
Ovarian carcinomas exhibited a higher cathepsin B activity than did normal ovaries. The plasma membrane fractions of ovarian cancers were enriched in the activities of both cathepsin and cysteine proteinase inhibitors. The ratio of cathepsin to the inhibitors in these fractions was higher at stage IV than at stage III of the disease, classified according to the Federation of International Gynecology and Obstetrics.

Wydawca

-

Rocznik

Tom

44

Numer

1

Opis fizyczny

p.113-120,fig.

Twórcy

autor
  • Wroclaw University of Medicine, Szewska 38-39, 50-139 Wroclaw, Poland
autor
autor
autor

Bibliografia

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  • 3. Kobayashi, H., Moniwa, N., Sugimura, M., Shinohara, H., Ohi, H. & Terao, T. (1993) Effects of membrane-associated cathepsin B on the activation of receptor-bound prouroki- nasc and subsequent invasion of reconsti­tuted basement membranes. Biochim. Bio- phys. Acta 1178, 55-62.
  • 4. Kobayashi, H., Ohi, H., Sugimura, M., Shino­hara, H., Fujii, T. & Terao, T. (1992) Inhibi­tion of in vitro ovarian cancer cell invasion by modulation of urokinase-type plasminogen activator and cathepsin B. Cancer Res. 52, 3610-3614.
  • 5. Schmalfeldt, B., Kuhn, W., Reuning, U., Pache, L., Dettmar, P., Schmitt, M., Janicke, F., Hofler, H. & Graeff, H. (1995) Primary tumor and metastasis in ovarian cancer differ in their content of urokinase-type plasmino­gen activator, its receptor, and inhibitors types 1 and 2. Cancer Res. 55, 3958-3963.
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Typ dokumentu

Bibliografia

Identyfikatory

Identyfikator YADDA

bwmeta1.element.agro-article-fe124565-54a4-4418-af47-7827ed002f69
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