A novel single-nucleotide polymorphism of the visfatin gene and its associations with performance traits in the chicken

• Autorzy: Han R-L , Lan X-Y , Zhang L-Z , Ren G , Jing Y-J , Li M-J , Zhang B , Zhao M , Guo Y-K , Kang X-T , Chen H
• Języki publikacji: EN

Abstrakty

EN

Visfatin is a peptide that is predominantly expressed in visceral adipose tissue and is hypothesized to be related to obesity and insulin resistance. In this study, a novel silent single-nucleotide polymorphism (SNP) was found in exon 7 of the chicken visfatin gene (also known as PBEF1) by single-stranded conformation polymorphism (SSCP) and DNA sequencing. In total, 836 chickens forming an F₂ resource population of Gushi chicken crossed with Anka broiler were genotyped by Xbal forced RFLP, and the associations of this polymorphism with chicken growth, carcass characteristics, and meat quality were analyzed. Significant associations were found between the polymorphism and 4-week body weight (BW4), 6-week body weight (BW6), 4-week body slanting length (BSL4), fat bandwidth (FBW), breast muscle water loss rate (BWLR) and breast muscle fiber density (BFD) (P < 0.05), as well as 4-week breastbone length (BBL4) (P < 0.01). These observations suggested that the polymorphism in exon7 of the visfatin gene had significant effects on the early growth traits of chicken.

Słowa kluczowe

PL

chicken; performance trait; visfatin; peptide; single nucleotide polymorphism; restriction fragment length polymorphism; single-strand conformation polymorphism; DNA sequencing; animal growth; chicken carcass; meat quality; carcass characteristics; genotype; breast muscle; insulin resistance

• Wydawca: -
• Czasopismo: Journal of Applied Genetics
• Rocznik: 2010
• Tom: 51
• Numer: 1
• Opis fizyczny: p.59-65,fig.,ref.

Twórcy

autor

Han R-L

• Shaanxi Key Laboratory of Molecular Biology for Agriculture, College of Animal Science and Technology, Northwest A and F University, Yangling, Shaanxi 712100, P.R. China
• Henan Research Center of Breeding Resources for Poultry, College of Livestock Husbandry and Veterinary Engineering, Henan Agricultural University, Zhengzhou, 450002, P.R. China

autor

Lan X-Y

• Shaanxi Key Laboratory of Molecular Biology for Agriculture, College of Animal Science and Technology, Northwest A and F University, Yangling, Shaanxi 712100, P.R. China

autor

Zhang L-Z

• Shaanxi Key Laboratory of Molecular Biology for Agriculture, College of Animal Science and Technology, Northwest A and F University, Yangling, Shaanxi 712100, P.R. China

autor

Ren G

• Shaanxi Key Laboratory of Molecular Biology for Agriculture, College of Animal Science and Technology, Northwest A and F University, Yangling, Shaanxi 712100, P.R. China

autor

Jing Y-J

• Shaanxi Key Laboratory of Molecular Biology for Agriculture, College of Animal Science and Technology, Northwest A and F University, Yangling, Shaanxi 712100, P.R. China

autor

Li M-J

• Shaanxi Key Laboratory of Molecular Biology for Agriculture, College of Animal Science and Technology, Northwest A and F University, Yangling, Shaanxi 712100, P.R. China

autor

Zhang B

• Shaanxi Key Laboratory of Molecular Biology for Agriculture, College of Animal Science and Technology, Northwest A and F University, Yangling, Shaanxi 712100, P.R. China

autor

Zhao M

• Shaanxi Key Laboratory of Molecular Biology for Agriculture, College of Animal Science and Technology, Northwest A and F University, Yangling, Shaanxi 712100, P.R. China

autor

Guo Y-K

• Shaanxi Key Laboratory of Molecular Biology for Agriculture, College of Animal Science and Technology, Northwest A and F University, Yangling, Shaanxi 712100, P.R. China

autor

Kang X-T

• Henan Research Center of Breeding Resources for Poultry, College of Livestock Husbandry and Veterinary Engineering, Henan Agricultural University, Zhengzhou, 450002, P.R. China

autor

Chen H

• Shaanxi Key Laboratory of Molecular Biology for Agriculture, College of Animal Science and Technology, Northwest A and F University, Yangling, Shaanxi 712100, P.R. China
• Institute of Cellular and Molecular Biology, Xuzhou Normal University, Xuzhou 221116, P.R. China

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