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Tytuł artykułu

Experimental infection of sheep with bovine immunodeficiency virus

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Treść / Zawartość

Warianty tytułu

Języki publikacji

EN

Abstrakty

EN
Five sheep were experimentally infected with bovine immunodeficiency virus (BIV). All animals seroconverted to BIV p26 core protein by 6 weeks after inoculation and developed persistent lymphocytosis. Proviral DNA has been continually detected only in one sheep and temporarily present in other two animals. All attempts to rescue the BIV from peripheral blood leukocytes of uninfected sheep have failed during experiment. The established model of bovine lentivirus infection in sheep provides valuable data to examine the pathogenesis of BIV and related retroviral infections.

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-

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Tom

44

Numer

1

Opis fizyczny

p.3-10,fig.

Twórcy

autor
  • National Veterinary Research Institute, 24-100 Pulawy, Poland
autor
autor

Bibliografia

  • 1. Amborski G.C., Lo J.L., Seger C.L.: Serological detection of multiple retroviral infections in cattle: bovine leukemia virus, bovine syncytial virus and bovine visna virus. Vet. Microbiol. 20, 247, 1988.
  • 2. Atkinson B., Liu Z.Q., Wood C.: Use of bacterial trpE fusion vectors to express and characterize the bovine immunodeficiency-like virus core protein. J. Virol. Meth. 36, 35, 1992.
  • 3. Baron T., Betemps D., Mallet F., Cheynet V., Levy D., Belli P.: Detection of bovine immunodeficiency-like infection in experimentally infected calves. Arch. Virol. 143, 181, 1998.
  • 4. Belloc C., Polack B., Schwartz-Cornil I., Levy D.: Bovine immunodeficiency virus: facts and questions. Vet. Res. 27, 395, 1996.
  • 5. Carpenter S., Miller L.D., Alexandersen S., Whetstone CA., VanDerMaaten M.J., Viuff B., Wannemuehler Y., Miller J.M., Roth J.A.: Characterization of early pathogenic effects after experimental infection of calves with bovine immunodeficiency-like virus. J. Virol. 66, 1074, 1992.
  • 6. Gonda M.A., Braun M.J., Carter S.G., Kast T.A., Bess J., Arthur L.O., VanDerMaaten M.J.: Characterization and molecular cloning of a bovine lentivirus related to human immunodeficiency virus. Nature 330, 388, 1987.
  • 7. Gonda M.A., Luther D., Fang S.E., Tobin G.J.: Bovine immunodeficiency virus: molecular biology and virus-host interaction. Virus Res. 32, 155, 1992.
  • 8. Hirai N., Kabeya H., Ohashi K., Sugimoto C., Onuma M.: lmmunomodulative effects of bovine immunodeficiency-like virus (BIV)-infection and mixed infection of BIV and bovine leukemia virus on sheep. Jpn. J. Vet. Res. 44, 153, 1997.
  • 9. Isaacson J.A., Roth J.A., Wood C., Carpenter S.: Loss of Gag-specific antibody reactivity in cattle experimentally infected with bovine immunodeficiency-like virus. Viral Immunol. 8, 27, 1995.
  • 10. Jacobs R.M., Smith H., Whetstone C.A., Suarez D., Fefferson B., Valli E.O.: Haematological and lymphocyte subset analyses in sheep inoculated with bovine immunodeficiency-like virus. Vet. Res. Com. 18, 471, 1994.
  • 11. Onuma M., Koomoto E., Furuyama H., Yasutomi Y., Taniyama H., lwai H., Kawakami Y.: lnfection and dysfunction of monocytes induced dy experimental inoculation of calves with bovine immunodeficiency-like virus. J. Acquired Immun. Defic. Syndrom. 5, 1009, 1992.
  • 12. Pifat D., Ennis W., Ward J., Oberste M., Gonda M.: Persistent infection of rabbits with bovine immunodeficiency-like virus. J. Virol. 66, 4518, 1992.
  • 13. Smith H.E and Jacobs R.M.: Serological evidence of bovine immunodeficiency virus infection in a sheep. Can. J. Vet. Res. 57, 305, 1993.
  • 14. Suarez D.L., ManDerMaaten M., Whetstone CA.: Improved early and long-term detection of bovine lentivirus by a nested polymerase chain reaction test in experimentally infected calves. Am. J. Vet. Res. 56, 579, 1995.
  • 15. Whetstone C.A., VanDerMaaten. M., Miller J.M.: A western blot assay for the detection of antibodies to bovine immunodeficiency-like virus in experimentally inoculated cattle, sheep and goats. Arch.Virol. 116, 119, 1991.
  • 16. VanDerMaaten M.J., Boothe A.D., Seger C.L.: Isolation of a virus from cattle with persistent lymphocytosis. J. Natl. Cancer Inst. 49, 1649, 1972.

Typ dokumentu

Bibliografia

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