Synthesis and application of chiral triazine condensing reagents prepared from esters of amino acids

• Autorzy: Kaminski Z. J. , Zajac K.J. , Jastrzabek K.
• Języki publikacji: EN

Abstrakty

EN

Treatment of cyanuric chloride with chiral amines or esters of chiral amino acids gave chiral 2,4-dichloro-6-alkylamino-1,3,5-triazines (2-5) in 49-69% yield, which were found useful as coupling reagents. Enantioselective activation and enantio­selective aminolysis in the presence of 2-5 was observed.

Słowa kluczowe

EN

chiral triazine; ester; application; treatment; tetrahydrofurane; 2,4-dichloro-6-alkylamino-1,3,5-triazine; synthesis; peptide synthesis; amino acid; chiral amino acid; cyanuric chloride; coupling reagent

• Wydawca: -
• Czasopismo: Acta Biochimica Polonica
• Rocznik: 2001
• Tom: 48
• Numer: 4
• Opis fizyczny: p.1143-1146,fig.

Twórcy

autor

Kaminski Z. J.

• Technical University of Lodz, 90-924 Lodz, Poland

autor

Zajac K.J.

autor

Jastrzabek K.

Bibliografia

• 1.Kaminski,Z.J., Markowicz, S.W., Kolesinska, B., Martynowski, D. & Glowka, M.L. (1998) Synth. Commun. 28, 2689-2696.
• 2.Kaminski,Z.J., Kolesinska, B., Markowicz, S.W. & Pokrzeptowicz, K. (1999) Pol. J. Chem. 73, 1965-1968.
• 3.Kaminski,Z.J., Kolesinska, B., Kaminska, J.E. & Gora, J. (2001) J. Org. Chem 66, 6276-6281.
• 4.Masala,S. & Taddei, M. (1999) Org. Lett 1, 1355-1357.
• 5.Kaminski,Z.J. (2000) Biopolymers 55, 140-165.