Effect of infection with bovine immunodeficiency virus and-or bovine leukaemia virus on lymphocyte blastogenesis to mitogens in sheep

• Autorzy: Stec J , Kuzmak J.
• Języki publikacji: EN

Abstrakty

EN

Lymphocyte blastogenesis was determined by ³H-thymidine incorporation assay after stimulation of the cell cultures with mitogens: Concanavalin A, phytohaemagglutitin, and pokeweed mitogen. BIV and/or BLV infection were associated with significant changes in lymphocyte blastogenesis to mitogens. The highest responses to all three mitogens were shown by 3 to 4.5 months after infection when compared to control animals, and thereafter were depressed at the end of the experiment Stimulated lymphocytes revealed in 20 - 50 fold increase in blastogenesis over background based on the unstimulated cells. These results demonstrated that a function impairement of lymphocytes can be observed in the course of BLV and/or BIV infection.

Słowa kluczowe

EN

bovine retrovirus; infection; sheep; cattle; mitogen; bovine leukemia virus; lymphocyte blastogenesis; bovine immunodeficiency virus; 3H-thymidine

• Wydawca: -
• Czasopismo: Bulletin of the Veterinary Institute in Puławy
• Rocznik: 2001
• Tom: 45
• Numer: 1
• Opis fizyczny: p.21-27,fig.

Twórcy

autor

Stec J

• National Veterinary Research Institute, 24-100 Pulawy, Poland

autor

Kuzmak J.

Bibliografia

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