Lack of carriers of citrullinaemia and DUMPS in Indian Holstein cattle

• Autorzy: Patel R K , Singh K M , Soni K J , Chauhan J B , Sambasiva Rao K R S
• Języki publikacji: EN

Abstrakty

EN

The present study investigated the occurrence of 2 autosomal recessive genetic diseases, bovine citrullinaemia and deficiency of uridine monophosphate synthase (DUMPS), in Indian Holstein cattle. The polymerase chain reaction-restriction fragment length polymorphism (PCR-RFLP) analysis was performed on a group of 642 animals, mainly HF and HF crossbred cattle, to identify carriers of these diseases. None of the animals were carriers of citrullinaemia or DUMPS. It is possible that with the mounting selection pressure, the international gene pool may diminish, and consequently the risk of dissemination of inherited defects will increase. It is therefore recommended to screen breeding bulls for their breed-specific genetic diseases before they are inducted in artificial insemination programmes, to minimize the risk.

Słowa kluczowe

EN

dissemination risk; deficiency; bovine citrullinaemia; Indian Holstein cattle; cattle; uridine monophosphate synthase; breed-specific genetic disease; polymerase chain reaction; animal disease; genetic disease; reaction-restriction fragment length polymorphism

• Wydawca: -
• Czasopismo: Journal of Applied Genetics
• Rocznik: 2006
• Tom: 47
• Numer: 3
• Opis fizyczny: p.239-242,ref.

Twórcy

autor

Patel R K

• R and D-Biotechnology, National Dairy Development Board, Anand-388 001, India

autor

Singh K M

• R and D-Biotechnology, National Dairy Development Board, Anand-388 001, India

autor

Soni K J

• R and D-Biotechnology, National Dairy Development Board, Anand-388 001, India

autor

Chauhan J B

• R and D-Biotechnology, National Dairy Development Board, Anand-388 001, India

autor

Sambasiva Rao K R S

• Centre for Biotechnology, Acharya Nagarjuna University, Nagarjunanagar, India

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