Spread and survival of promiscuous IncP-1 plasmids

• Autorzy: Adamczyk M. , Jagura-Burdzy G.
• Języki publikacji: EN

Abstrakty

EN

Plasmids classified to the IncP-1 incompatibility group belong to the most stably maintained mobile elements among low copy number plasmids known to date. The re­markable persistence is achieved by various tightly controlled stability mechanisms like active partitioning, efficient conjugative transfer system, killing of plasmid-free segregants and multimer resolution. The unique feature of IncP-1 plasmids is the cen­tral control operon coding for global regulators which control the expression of genes involved in vegetative replication, stable maintenance and conjugative transfer. The multivalent regulatory network provides means for coordinated expression of all plasmid functions. The current state of knowledge about two fully sequenced plasmids RK2 and R751, representatives of the IncP-1a and IncP-1β subgroups, is presented.

Słowa kluczowe

EN

classification; spread; gene expression; IncP-1 plasmid; plasmid; central control region; global regulation; distribution; plasmid function; survival

• Wydawca: -
• Czasopismo: Acta Biochimica Polonica
• Rocznik: 2003
• Tom: 50
• Numer: 2
• Opis fizyczny: p.425-453,fig.

Twórcy

autor

Adamczyk M.

• Polish Academy of Sciences, A.Pawinskiego 5a, 02-106 Warsaw, Poland

autor

Jagura-Burdzy G.

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