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2001 | 48 | 4 |

Tytuł artykułu

Mechanisms of plasmid stable maintenance with special focus on plasmid addiction systems

Warianty tytułu

Języki publikacji

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Abstrakty

EN
The stable inheritance of bacterial plasmids is achieved by a number of different mechanisms. Among them are resolution of plasmid oligomers into monomers, active plasmid partitioning into dividing cells and selective killing of plasmid-free segre- gants. A special focus is given to the last mechanism. It involves a stable toxin and an unstable antidote. The antidotes neutralize their cognate toxins or prevent their syn­thesis. The different decay rates of the toxins and the antidotes underlie molecular mechanisms of toxin activation in plasmid-free cells. By eliminating of plasmid-free cells from the population of plasmid-bearing ones the toxin-antidote couples therefore act as plasmid addiction systems.

Wydawca

-

Rocznik

Tom

48

Numer

4

Opis fizyczny

p.1003-1023,fig.

Twórcy

  • Polish Academy of Sciences, A.Pawinskiego 5a, 02-106 Warsaw, Poland
autor

Bibliografia

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