Mechanizm dzialania estrogenow na osrodki centralnego ukladu nerwowego regulujace zachowanie seksualne samic

• Autorzy: Kedzierski W

Warianty tytułu

EN

Mechanism of the action of estrogens on nerve-centers in the brain that regulate the sexual behavior of females

• Języki publikacji: PL

Abstrakty

EN

The study discusses molecular mechanisms of the action of estrogens (E) in the brain and their effect on sexual behavior in females. E increase the synthesis of the neuromediators: oxytocin and dopamine in the brain. E also influence K+ channel activity in neurons. Specific intracellular E receptors exist in the neurons. These receptors bind E and then activate a regulatory mechanism dependent on the protein G complex and on the cyclical AMP response element binding proteins (CREB). As a result, synaptic activity of the neurons increase and the expression of the brain-derived neurotrophic factor (BDNF) gene also take place. Moreover, E stimulate the synthesis of the sex hormone binding globulin (SHBG). SHBG plays a role as a steroids transporter and also as a signaling substance in the brain.

Słowa kluczowe

PL

fizjologia zwierzat; samice; zachowania seksualne; regulacja; estrogeny; oddzialywanie na organizm; mechanizm dzialania; uklad nerwowy osrodkowy; mozg

• Wydawca: -
• Czasopismo: Medycyna Weterynaryjna
• Rocznik: 2009
• Tom: 65
• Numer: 10
• Opis fizyczny: s.674-678,bibliogr.

Twórcy

autor

Kedzierski W

• Uniwersytet Przyrodniczy w Lublinie, ul.Akademicka 12, 20-033 Lublin

Bibliografia

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