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2009 | 65 | 01 |

Tytuł artykułu

Rola cirkowirusa PCV2 w wywolywaniu zaburzen w rozrodzie swin

Warianty tytułu

EN
Role of circovirus PCV2 in reproductive failure in swine

Języki publikacji

PL

Abstrakty

EN
Porcine reproductive disease associated with PCV2 (PRD-PCV2), as one of several syndromes of the porcine circovrirus diseases (PCVD), was characterized. Differences in relation to the Porcine Parvovirus infection, also causing reproductive failure in swine, but to a larger extent, were presented. Diagnostic tests for PCV2 identification and antibody detection were enumerated. The transplacental infection of the fetus by the viremic sow was the only way of PRD-PCV2 proliferation. The ability of PCV2 to replicate in the fetuses and cause pathologic abnormalities was demonstrated. The heart of the fetuses contained the highest virus titre and the highest number of antigen positive cells. Gross lesions observed in dead mummified or not mummified fetuses were described - the most characteristic were those in the heart. The myocardium, which was hypertrophic, showed multiple and irregular pale areas that corresponded to histological lesions of necrosis. The relationship between a herd of swine with PMWS and PRD-PCV2 as the mechanism of continuous infection in sows, fetuses and pigs growing with PMWS was presented. It was demonstrated that countering the infection is a complex task requiring the vaccination of sows against accompanying infections and against PCV2 as well as an appropriate management of the farm aimed at ensuring the welfare of animals.

Wydawca

-

Rocznik

Tom

65

Numer

01

Opis fizyczny

s.6-8,bibliogr.

Twórcy

  • Panstwowy Instytut Weterynaryjny - Panstwowy Instytut Badawczy, Al.Partyzantow 57, 24-100 Pulawy
autor

Bibliografia

  • 1. Allan G. M., Ellis J. A.: Porcine circoviruses: a review. J. Vet. Diagn. Investi. 2000, 12, 3-14.
  • 2. Allan G. M., Kennedy S., McNeilly F., Foster J. C., Ellis J. A., Krakowka S. J., Meehan B. M., Adair B. M.: Experimental reproduction of severe wasting disease by co-infection of pigs with porcine circovirus and porcine parvovirus. J. Comp. Pathol. 1999a, 121, 1-11.
  • 3. Blanchard P., Mahe D., Cariolet R., Keranflech A., Baudouard M. A., Cordioli P., Albina E., Jestin A.: Protection of swine against post-weaning multisystemic wasting syndrome (PMWS) by porcine circovirus type 2 (PCV2) proteins. Vaccine 2003a, 21, 4565-4575.
  • 4. Blanchard P., Mahe D., Cariolet R., Truong C., Le Dimna M., Arnauld C., Rose N., Eveno E., Albina E., Madec F., Jestin A.: An ORF2 protein-based ELISA for porcine circovirus type 2 antibodies in post-weaning multisystemic wasting syndrome. Vet. Microbiol. 2003b, 94, 183-194.
  • 5. Calsamiglia M., Segalés J., Quintana J., Rosell C., Domingo M.: Detection of porcine circovirus types 1 and 2 in serum and tissue samples of pigs with and without postweaning multisystemic wasting syndrome. J. Clini. Microbiol. 2002, 40, 1848-1850.
  • 6. Hassings A. G., Kristensen C. S., Baebko P., Wachmann H.: Effect of sow on the mortality of pigs after weaning in PMWS herds, [w:] Proc. Internat. Pig Veterinary Society Congress, Hamburg 2004, s. 76.
  • 7. Krakowka S., Ellis J., McNeilly F., Waldner C., Rings M., Allan G.: Commercial mycoplasmal vaccines and potentiation of PCV2 infection, [w:] Proc. 36th Ann. Meeting Am. Assoc. of Swine Veterinarians, Toronto 2005, s. 259-261.
  • 8. Mankertz A., Person F., Mankertz J., Blaess G., Buhk H.-J.: Mapping and characterization of the origin of DNA replication of porcine circovirus. J. Virology 1997, 71, 2562-2566.
  • 9. McNair I., Marshall M., McNeilly F., Botner A., Ladekjaer-Mikkelsen A. S., Vincent I., Herrmann B., Sánchez R., Rhodes C.: Interlaboratory testing of porcine sera for antibodies to porcine circovrius type 2. J. Vet. Diagn. Investi. 2004, 16, 164-166.
  • 10. McNeilly F., Kennedy S., Moffett D., Meehan B. M., Foster J. C., Clarke E. G., Ellis J. A., Haines D. M., Adair B. M., Allan G. M.: A comparison of in situ hybridization and immunohistochemistry for the detection of a new porcine circovirus in formalin-fixed tissues from pigs with post-weaning multisystemic wasting syndrome (PMWS). J. Virol. Methods 1999, 80, 123-128.
  • 11. O'Connor B., Gauvreau H., West K., Bogdan J., Ayroud M., Clark E. G., Konoby C., Allan G., Ellis J. A.: Multiple porcine circovirus 2-associated abortions and reproductive failure in a multisite swine production unit. Can. Vet. J. 2001, 42, 551-553.
  • 12. Okuda Y., Ono M., Yazawa S., Shibata I.: Experimental reproduction of postweaning multisystemic wasting syndrome in cesarean-derived, colostrums-deprived piglets inoculated with porcine circovirus type 2 (PCV2): investigation of quantitative PCV2 distribution and antibody responses. J. Vet. Diagn. Invest. 2003, 15, 107-114.
  • 13. Park J.-S., Kim J., Ha Y., Jung K., Choi C., Lim J.-K., Kim S.-H., Chae C.: Birth abnormalities in pregnant sows infected intranasally with porcine circovirus 2. J. Comp. Path. 2005, 132, 139-144.
  • 14. Pensaert M. B., Sanchez Jr. R. E., Ladekjaer-Mikkelsen A.-S., Allan G. M., Nauwynck H. J.: Viremia and effect of fetal infection with porcine viruses with special reference to porcine circovirus 2 infection. Vet. Microbiol. 2004, 98, 175-183.
  • 15. Rodriguez-Arrioja G. M., Segalés J., Calsamiglia M., Resendes A. R., Balasch M., Plana-Duran J., Casal J., Domingo M.: Dynamics of porcine circovirus type 2 infection in a herd of pigs with postweaning multisystemic wasting syndrome. Am. J. Vet. Res. 2002, 63, 354-357.
  • 16. Sánchez Jr. R. E., Hans J., Nauwynck J., McNeilly F., Allan G. M., Pensaert M. B.: Porcine circovirus 2 infection in swine fetuses inoculated at different stages of gestation. Vet. Microbiol. 2001, 83, 169-176.
  • 17. Segalés J., Allan G. M., Domingo M.: Porcine circovirus diseases. Anim. Health Res. Rev. 2005, 6, 1-24.
  • 18. Sibila M., Calsamiglia M., Segalés J., Blanchard P., Badiella L., Le Dimna M., Jestin A., Domingo M.: Use of a polymerase chain reaction assay and an ELISA to monitor porcine circovirus type 2 infection in pigs from farms with and without postweaning multisystemic wasting syndrome. Am. J. Vet. Res. 2004, 65, 88-92.
  • 19. Truszczyński M., Pejsak Z.: Mechanizm chorobotwórczości cirkowirusów ze szczególnym uwzględnieniem poodsadzeniowego, wielonarządowego zespołu wyniszczającego świń i wskazania do jego zwalczania. Medycyna Wet. (w druku).
  • 20. Truszczyński M., Pejsak Z.: Parwowirus świń, najważniejsza zakaźna przyczyna zamierania zarodków i płodów. Medycyna Wet. 2008, 64, 10-13.
  • 21. West K. H., Bystrom J. M., Wojnarowicz C., Shantz N., Jacobson M., Allan G. M., Haines D. M., Clark E. G., Krakowka S., McNeilly F., Konoby C., Martin K., Ellis J. A.: Myocarditis and abortion associated with intrauterine infection of sows with porcine circovirus 2. J. Vet. Diag. Invest. 1999, 11, 530-532.

Typ dokumentu

Bibliografia

Identyfikatory

Identyfikator YADDA

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