Bierna i czynna odpornosc przeciw chorobom zakaznym u oseska do okresu okoloodsadzeniowego

• Autorzy: Truszczynski M , Pejsak Z.

Warianty tytułu

EN

Passive and active immunity against infectious diseases of suckling until weaning

• Języki publikacji: PL

Abstrakty

EN

Pre-weaning mortality in domestic animals results in a significant loss in animal production. Immunizing pregnant dams before parturition is practiced in order to prevent or decrease losses from various threatening diseases. The transferal of maternal immunity to offspring depends on the type of animal species and may occur via the placenta and colostrum or only through colostrum. Maternal, passive immunity of sucklings lasts for several weeks only and decreases in time, therefore young animals must be vaccinated in order to be protected against infectious diseases. Maternal antibodies present in suckling block antigenic epitopes of the vaccine antigens and interfere with their efficacy and, thus, the appropriate time for vaccinating is not easy to determine. It should occur early in the process of maturation, yet not when the level of maternal antibodies is very high in order to facilitate minimizing the immunological window (also know as the window of susceptibility) which exists between decreased maternal immunity and the inefficacy of post-vaccine protection. Maternal antibodies do not interfere with the activity of cellular immunity. In the case of humeral immunity the priming of B lymphocytes, which gain immunological memory, occurs despite the blocking of epitopes and so the ensuing vaccine leads to a more intensive production of antibodies and a higher activity of T lymphocytes. Additionally, the appropriate choice of adjuvant in inactivated vaccines is crucial for the immunogenic effect of early vaccination in offspring.

Słowa kluczowe

PL

odpornosc czynna; odpornosc matczyna; noworodki; szczepienia ochronne; choroby zakazne; odpornosc bierna; odpornosc zwierzat; okres neonatalny; okres okoloodsadzeniowy

• Wydawca: -
• Czasopismo: Medycyna Weterynaryjna
• Rocznik: 2007
• Tom: 63
• Numer: 10
• Opis fizyczny: s.1142-1145,rys.,tab.,bibliogr.

Twórcy

autor

Truszczynski M

• Panstwowy Instytut Weterynaryjny - Panstwowy Instytut Badawczy, Al.Partyzantow 57, 24-100 Pulawy

autor

Pejsak Z.

Bibliografia

• 1.Anon.: Meat and Livestock Commission. Pig Year-book 2001, Milton Keynes, UK.
• 2.Bohl E. H., Saif L. J.: Passive immunity against enteric viral infections of piglets, [w:] The Mucosal Immune System. Proceedings of a seminar in the EEC programme coordination of agricultural research on protection of the young animal against perinatal diseases. Bristol, UK, September 9-11, 1980 (Ed. F. J. Bourne). Martinus Nijhoff Publishers. The Hague 1981, s. 259-282.
• 3.Chappuis C.: Neonatal immunity and immunisation in early age: lesson from veterinary medicine. Vaccine 1998, 16, 1468-1472.
• 4.Drew M. D., Owens B. D.: The provision of passive immunity to colostrums-deprived piglets by bovine or porcine serum immunoglobulins. Can. J. Anim. Sci. 1988, 68, 1277-1284.
• 5.Gillespie J. H., Scott F. W.: Feline viral infections. Adv. Vet. Sci. 1973, 17, 163-200.
• 6.Klobasa F., Werhahn E., Butler J. E.: Regulation of humoral immunity in the piglet by immunoglobulins of maternal origin. Res. Vet. Sci. 1981, 31, 195-206.
• 7.Martelli P., Terreni M., Guazetti S., Cavirani S.: Antibody response to Mycoplasma hyopneumoniae infection in vaccinated pigs with or without maternal antibodies induced by sow vaccination. J. Vet. Med. B. 2006, 53, 229-233.
• 8.Morein B., Abusugra I., Blomqvist G.: Immunity in neonates. Veterinary Immunology and Immunopathology 2002, 87, 207-213.
• 9.Rooke J. A., Bland I. M.: The acquisition of immunity in the new-born piglet. Livestock Prod. Sci. 2002, 78, 13-23.
• 10.Schultz R. D.: Transfer of humoral and cellular immunity through colostrums. Merial Europ. Vaccinology Symp. Abstr Book Acomparative approach to early life vaccination, Athens, Greece 2-4.11.2006, s. 55.
• 11.Siegrist C.-A.: Mechanisms by which maternal antibodies influence infant vaccine responses: review of hypotheses and definition of main determinants. Vaccine 2003, 21, 3406-3412.
• 12.Siegrist C.-A.: Neonatal and early life vaccinology. Vaccine 2001, 19, 3331- -3346.
• 13.Truszczyñski M., Pejsak Z.: Czynniki chorobotwórczoœci bakterii a skutecznoœæ szczepionek dla świñ. Medycyna Wet. 2006, 62, 493-497.
• 14.Truszczyñski M., Pejsak Z.: Szczepionki nowej generacji. Medycyna Wet. 2006, 62, 855-859.
• 15.Zuffa A.: Induction of biological protection in pigs against infection with Aujeszky disease virus by vaccination with large doses of live or inactivated vaccines. Vet. Med. Praha 1986, 31, 83-94.