Genetic immunization of ducks for production of antibodies specific to Helicobacter pylori UreB in egg yolks

• Autorzy: Kazimierczuk K. , Cova L. , Ndeboko B. , Szczyrk U. , Targosz A. , Brzozowski T. , Sirko A.
• Języki publikacji: EN

Abstrakty

EN

Following genetic immunization of laying ducks with a plasmid expressing Helicobacter pylori UreB (large subunit of urease), IgY against UreB were obtained from egg yolks. These polyclonal and monospecific IgY antibodies are of higher-titer and specifically recognize recombinant H. pylori urease purified from Escherichia coli. To our knowledge this is the first report describing generation of IgY antibodies directed against antigens of H. pylori by DNA-based immunization.

Słowa kluczowe

EN

production; egg yolk; duck; antigen; laying duck; genetic immunization; urease large subunit; IgY antibody; DNA immunization; Helicobacter pylori; urease; antibody

• Wydawca: -
• Czasopismo: Acta Biochimica Polonica
• Rocznik: 2005
• Tom: 52
• Numer: 1
• Opis fizyczny: p.261-266,fig.,ref.

Twórcy

autor

Kazimierczuk K.

• Polish Academy of Sciences, A.Pawinskiego 5A, 02-106 Warsaw, Poland

autor

Cova L.

autor

Ndeboko B.

autor

Szczyrk U.

autor

Targosz A.

autor

Brzozowski T.

autor

Sirko A.

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