Effect of the coupled administration of Lydium-KLP or methisoprinol and respisure on the health status and prevention of mycoplasmal pneumonia of swine in large-scale commercial breeding

• Autorzy: Procajlo Z , Szweda W. , Mikulska-Skupien E. , Platt-Samoraj A.
• Języki publikacji: EN

Abstrakty

EN

The study was aimed on determining the clinical protective value of Lydium-KLP and Methisoprinol in the prevention of respiratory system diseases, as well as their effect on the health status of pigs in large-scale commercial breeding and on the improvement of in the effectiveness of specific immunoprophylaxis of mycoplasmal pneumonia of in swine (MPS). Piglets at the age of 7 d were divided into eight groups of 25-30 piglets each. On days 7 and 21 of life they were immunised with Respisure vaccine (group I) or administrated Lydium-KLP or Methisoprinol (groups IV and VII). In other groups, Lydium-KLP or Methisoprinol were given simultaneously (groups II and V) or 48 h before immunisation with Respisure (groups III and VI). Control piglets were administrated PBS (group C). Clinical observations as well as post-slaughter and animal husbandry analyses indicated that the simultaneous administration of Lydium-KLP or Methisoprinol with Respisure gives better results in comparison to immunisation- only with Respisure. The statistically-significant differences were found in the mean percentage of meatiness between groups receiving Methisoprinol with or 48 h before Respisure and control group, as well as in the point evaluation of lesions in the lungs between groups receiving Lydium-KLP with Respisure and Methisoprinol 48 h before Respisure and control group. The study demonstrated the beneficial effect of coupled administration of Lydium-KLP or Methisoprinol and Respisure on the improvement of health status and the productive performance of pigs, as well as on the effectiveness of specific immunoprophylaxis of MPS in large- scale commercial breeding. The most beneficial variants of coupled administration were the simultaneous application of Lydium- KLP and Respisure, and Methisoprinol application 48 h before immunisation with Respisure.

Słowa kluczowe

EN

pig; animal breeding; commercial breeding; large-scale commercial breeding; health status; prevention; pneumonia; mycoplasmosis; respiratory system; animal disease; Lydium KLP; methisoprinol; prophylaxis

• Wydawca: -
• Czasopismo: Bulletin of the Veterinary Institute in Puławy
• Rocznik: 2010
• Tom: 54
• Numer: 1
• Opis fizyczny: p.9-14,ref.

Twórcy

autor

Procajlo Z

• University of Warmia and Mazury in Olsztyn, 10-718 Olsztyn, Poland

autor

Szweda W.

autor

Mikulska-Skupien E.

autor

Platt-Samoraj A.

Bibliografia

• 1. Bartnicka B., Kondracki M.: The influence of application of immunomodulators for some mechanisms of cellular protection in newborn piglets. Medycyna Wet 1984, 40, 693-695.
• 2. Benda V., Mádr P., Cermák P.: Adjuvant effects of glucan on antibody formation in swine. Berl Munch Tierarztl Wochenschr 1992, 105, 95-96.
• 3. Blecha F.: Immunomodulation: a means of disease prevention in stressed livestock. J Anim Sci 1988, 66, 2084-2090.
• 4. Dohoo I., Montgomery M.: A field trial to evaluate a Mycoplasma hyopneumoniae vaccine: effects on lung lesions and growth rates in swine. Can Vet J 1996, 37, 299-302.
• 5. Goodwin R.F., Whittlestone P.: Enzootic pneumonia of pigs: Immunization attempts inoculating Mycoplasma suipneumoniae antigen by various routes and with different adjuvants. Br Vet J 1973, 129, 456-464.
• 6. Jung K., Ha Y., Ha S.K., Han D.U., Kim D.W., Moon W.K., Chae C.: Antiviral effect of Saccharomyces cerevisiae beta-glucan to swine influenza virus by increased production of interferon-gamma and nitric oxide. J Vet Med B 2004, 51, 72-76.
• 7. Kiczka W.: From lysozyme monomer to lysozyme dimer. Życie Wet 1994, 69, 131-136.
• 8. Kołodziejczyk P., Loda M., Kawczyński R., Czapla R.: Efficacy of specific prophylactics in the eradication of pneumonia in pigs caused by Mycoplasma hyopneumoniae. Medycyna Wet 2002, 58, 448-452.
• 9. Kołodziejczyk P., Pejsak Z.: Biological properties of Mycoplasma hyopneumoniae, agent of mycoplasmal pneumonia in swine. Medycyna Wet 2004, 60, 341-344.
• 10. Kołodziejczyk P., Stankiewicz I., Porowski M., Pejsak Z.: Effectiveness of Lydium KLP in treating coliform mastitis in sows and mixed respiratory infections in swine. Medycyna Wet 2002, 58, 270-274.
• 11. Krakowski L., Krzyżanowski J., Wrona Z.: Changes within particular parameters of nonspecific immunity in piglets in the post-natal period. Medycyna Wet 1998, 54, 750-752.
• 12. Krakowski L., Krzyżanowski J., Wrona Z., Kostro K., Siwicki A.K.: The influence of nonspecific immunostimulation of pregnant sows on the immunological value of colostrum. Vet Immunol Immunopathol 2002, 87, 89-95.
• 13. Kyriakis S.C., Saoulidis K., Lekkas S., Miliotis Ch.C., Papoutsis P.A., Kennedy S.: The effects of immunomodulation on the clinical and pathological expression of postweaning multisystemic wasting syndrome. J Comp Pathol 2002, 126, 38-46.
• 14. Le Grand A., Kobisch M.: Comparaison de l'utilisation d'un vaccin et d'un traitement antibiotique séquentiel dans un élevage infecté par Mycoplasma hyopneumoniae. Vet Res 1996, 27, 241-253.
• 15. Maes D., Deluyker H., Verdonck M., Castryck F., Miry C., Vrijens B., Verbeke W., Viaene J., de Kruif A.: Effect of vaccination against Mycoplasma hyopneumoniae in pig herds with an all-in/out production system. Vet Quart 1996, 18, 143-168.
• 16. Maes D., Segales J., Meyns T., Sibila M., Pieters M., Haesebrouck F.: Control of Mycoplasma hyopneumoniae infections in pigs. Vet Microbiol 2008, 126, 297-309.
• 17. Maes D., Verdonck M., Deluyker H., de Kruif A.: Enzootic pneumonia in pigs. Vet Quart 1996, 18, 104-109.
• 18. Markowska-Daniel I.: Stimulation of immune responses using natural and chemical immunomodulators in therapy and prophylaxis. Medycyna Wet 1991, 47, 306-310.
• 19. Markowska-Daniel I., Glapiak L.: Influence of Inmodulen on the efficacy of vaccination against Mycoplasma hyopneumoniae. Magazyn Wet 2005, Supplement, 105-108.
• 20. Markowska-Daniel I., Pejsak Z.: The influence of iron and isoprinosine on haematological parameters in piglets. Medycyna Wet 2002, 58, 127-133.
• 21. Markowska-Daniel I., Pejsak Z., Tarasiuk K., Błaszczyk B., Szmigielski S., Pulverer G.: Application of Propionibacterium avidum (PA) KP-40 in stimulation of pigs immunized with selected viral antigens. Medycyna Wet 1992, 48, 361-363.
• 22. Markowska-Daniel I., Stankiewicz I., Wałachowski M., Pejsak Z.: Influence of iron and isoprinosine application on piglet health. Medycyna Wet 2002, 58, 45-48.
• 23. Markowska-Daniel I., Żmudzki J., Pejsak Z.: Influence of iron and isoprinosine on immunology parameters in piglets. Medycyna Wet 2002, 58, 598-602.
• 24. Megid J., Cremonini D.N., Leomil H.: Distribution of rabies virus in infected mice vaccinated and submitted to P. acnes as immunomodulator. Comp Immunol Microbiol Infect Dis 2002, 25, 237-248.
• 25. Pejsak Z., Janicka K., Stadejek T.: Efficacy of specific and unspecific prophylaxis for controlling porcine reproductive and respiratory syndrome. Medycyna Wet 2005, 61, 417-421.
• 26. Pejsak Z., Kiczka W., Jękot T., Kwaczyński R., Loda M., Rutkowski W., Wojciech J., Nadolny M.: Estimation of Lydium-KLP usefulness in treatment of some bacterial pig diseases in field conditions. Życie Wet 1994, 69, 162-164.
• 27. Pointon A.M., Byrt D., Heap P.: Effect of enzootic pneumonia of pigs on growth performance. Aust Vet J 1985, 62, 13-18.
• 28. Stipkovits L., Ovos I., Marca J., Tares J.: Comparative effect of Inmodulen compared with conventional antibiotic therapy against enzootic pneumonia. Proceedings of IPVS Congress, Birmingham, 1998, p. 291.
• 29. Straw B.E., Tuovinen V.K., Bigras-Poulin M.: Estimation of the cost of pneumonia in swine herds. J Am Vet Med Assoc 1989, 195, 1702-1706.
• 30. Tarasiuk K., Pejsak Z., Stadejek T., Błaszczyk B.: Efficacy of immunoprophylaxis in the control of mycoplasmal pneumoniae of swine. Medycyna Wet 1992, 48, 402-405.
• 31. Wongnarkpet S., Morris R.S., Pfeiffer D.U.: Field efficacy of a combined use of Mycoplasma hyopneumoniae and Actinobacillus pleuropneumoniae vaccines in growing pigs. Prev Vet Med 1999, 39, 13-24.