PL EN


Preferencje help
Widoczny [Schowaj] Abstrakt
Liczba wyników
1998 | 40 |

Tytuł artykułu

Genotoxicity of pentachlorophenol revealed by Allium chromosome aberration assay

Warianty tytułu

Języki publikacji

EN

Abstrakty

EN
Pentachlorophenol (PCP) is known to be a very effective biocide, used very widely a few years ago. Eventually its use was stopped in many countries when it was shown that PCP is highly toxic, especially to water organisms, and to some land animals and plants. However, PCP is still present in the environment, mostly as a metabolic product of some pesticides. Roots of shallot (Allium ascalonicum auct.) were exposed to different concentrations of PCP: 0.001, 0.01, 0.1 and 1 mg/dm3 for 24 h. The tested solutions were adjusted to pH 3.0, 6.0 or 8.0. Root tip cells were analyzed either after 24 h of treatment or after treatment and 48 h recovery in water. Genotoxic effects of PCP in root tip cells were noted, the extent of which depended on the PCP concentration and pH. Chromosome and mitotic aberrations were found, including the significant occurrence of micronuclei, chromosome bridges and multipolar cells.

Wydawca

-

Rocznik

Tom

40

Opis fizyczny

p.85-90,fig.

Twórcy

autor
  • University of Zagreb, Rooseveltov trg 6, 10000 Zagreb, Croatia
autor

Bibliografia

  • Bellani, L. M. 1994. Cytological effects of different pH on Allium roots. Advances in Horticultural Science 8: 278-283.
  • Chand, S. 1980. Effects of herbicide Pentachlorophenol on mitosis and DNA synthesis in Nigella sativa L. Acta Botanica Indica 8(2): 219-223.
  • Erlich, W. 1990. The effect of pentachlorophenol and its metabolite tetrachlorohydroquinone on cell growth and the induction of DNA damage in Chinese hamster ovary cell. Mutation Research 244(4): 299-302.
  • Feind, D., F. J. Zieris, and W. Huber. 1988. Effects of sodium pen- tachlorophenate on the ecology of a freshwater model ecosystem. Environmental Pollution 50: 211-223.
  • Fisher, S. W. 1990. The pH dependent accumulation of PCP in aquatic microcosm with sediment. Aquatic Toxicology 18:199-218.
  • Fiskesjö, G. 1985. The Allium-test as a standard in environmental monitoring. Hereditas 102: 99-112.
  • Fiskesjö, G. 1997. Allium test for screening chemicals; evaluation of cytological parameters. In: W. Wang, J. W. Gorsuch, and J. S. Hughes [eds.], Plants for Environmental Studies, 308-333. Lewis Publishers, Boca Raton, New York.
  • Fiskesjö, G., and A. Levan. 1993. Evaluation of the first ten MEIC chemicals in the Allium-test. ALTA 21: 139-149.
  • Jansson, K., and V. Jansson. 1991. Induction of mutation in V79 Chinese hamster cells by tetrachlorohydroquinone, a metabolite of pentachlorophenol. Mutation Research 260:83-87.
  • Klobučar, G. I. V., J. Lajtner, and R. Erben. 1997. Lipid peroxidation and histopathological changes in the digestive gland of a freshwater snail Planorbarius corneus L. (Gastropoda, Pulmonata) exposed to chronic and sub-chronic concentration of PCP. Environmental Contamination and Toxicology 58: 128-134.
  • Levan, A. 1938. The effect of colchicine on root mitosis in Allium. Hereditas 24: 471-486.
  • Mozzafari, F. D. S., and P. B. Gahan. 1978. Chromosome aberrations and ageing root meristem. Annals of Botany 42: 1161-1170.
  • Nielsen, M. H., and J. Rank. 1994. Screening of toxicity and genotoxicity in waste water by the use of the Allium test. Hereditas 121: 249-254.
  • Rank, J., and M. H. Nielsen. 1997. Allium cepa anaphase-telophase root tip chromosome aberration assay on N-methyl-N- nitrosourea, maleic hydrazide, sodium azide, and ethyl methanesulfonate. Mutation Research 390: 121-127.
  • Roy, S., and O. Hänninenh. 1994. Pentachlorophenol: Uptake/elimination kinetics and metabolism in an aquatic plant, Eichhornia crassipes. Environmental Toxicology and Chemistry 13: 763-773.
  • Sandermann, H. Jr. 1988. Mutagenic activation of xenobiotics by plant enzymes. Mutation Research 197: 183-194.
  • Sharma, A. K., and A. Sharma. 1972. Chromosome Technigues - Theory and Practice. University Park Press, Butterworths, London.
  • Shofer, S. L, and R. S. Tjeerdema. 1993. Comparative disposition and biotransformation in the oyster (Crassostrea gigas) and abalone (Haliotis fulgens). Pesticide Biochemistry and Psysiology 46: 85-95.
  • Tjeerdema, R. S., T. W-M. Fan, R. M. Higashi, and D. G. Crosby. 1991. Sublethal effects of pentachlorophenol in the abalone (Haliotis rufescens) as measured by in vivo 31P NMR spectroscopy. Journal of Biochemistry and Toxicology 6(1): 45-55.
  • Tjeerdema, R. S., and D. G., Crosby. 1992. Disposition and biotrans- fomation of pentachlorophenol in the red abalone (Haliotis rufescens). Xenobiotica 22(6): 681-690.
  • Witte, I., U. Juhl, and W. Butte. 1985. DNA-damaging properties and cytotoxicity in human fibroblasts of tetrachlorohydroquinone, a pentachlorophenol metabolite. Mutation Research 145: 71-75.
  • World Health Organization. 1987. Pentachlorophenol. Environmental Health Criteria 71, Geneva.

Typ dokumentu

Bibliografia

Identyfikatory

Identyfikator YADDA

bwmeta1.element.agro-article-daf3d05f-5f09-4729-951b-9d4318787fbb
JavaScript jest wyłączony w Twojej przeglądarce internetowej. Włącz go, a następnie odśwież stronę, aby móc w pełni z niej korzystać.