The significance of the level of antibodies in the evaluation of the effects of treatment of toxocariasis

• Autorzy: Malafiej E , Spiewak E.
• Języki publikacji: EN

Abstrakty

EN

The observation of a group of 168 children treated for toxocariasis shows that the most frequent symptoms at the time of the physical examination were abdominal pains - 41 %; headache was observed in 12% cases. Eosinophilia was found in 9.2% cases. The final diagnosis was based on the results of serological investigation. The level of IgG antibodies was established by the ELISA method using the excretory - secretory antigen of Toxocara canis larvae. A few years of studies lead to the observation that after treatment the return of the level of antibodies to normal is a very slow process - positive results are found in 57% of patients even after 4 to 7 years and the decrease of the mean titre of antibodics does not exceed 45%. The observations show that examination of the level of antibodies in the way hitherto applied does not provide a satisfactory indication of the positive effect of treatment. Therefore, it is necessary to develop a system of additional laboratory tests that will altow a faster evaluation of the effects of treatment of this disease.

Słowa kluczowe

EN

parasitic disease; parasite; toxocariasis; treatment; antibody level; ELISA test; IgG antibody; larva; Toxocara canis

• Wydawca: -
• Czasopismo: Wiadomości Parazytologiczne
• Rocznik: 2001
• Tom: 47
• Numer: 4
• Opis fizyczny: p.805-810,fig.,ref.

Twórcy

autor

Malafiej E

• Polish Mother Memorial Hospital and Research Institute, 93-338 Lodz, 281-289 Rzgowska Street, Poland

autor

Spiewak E.

Bibliografia

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