Associations between the microsatellite DNA sequence in the IGF1 gene, polymorphism in the ESR gene and selected reproduction traits in F1 [Zlotnicka Spotted x Polish Large White] sows

• Autorzy: Korwin-Kossakowska A , Sender G. , Kuryl J.
• Języki publikacji: EN

Abstrakty

EN

In 53 F1 sows (Zlotnicka Spotted boars × Polish Large White sows) the insulin-like growth factor 1 (IGF1) and estrogen receptor (ESR) genes were assessed as candidate genes for total number of piglets born (TNB), number of piglets born alive (NBA), litter weight at birth (LWB), litter weight at weaning (LWW), number of piglets weaned (NPW), average piglet weight at weaning (AWW) and gestation length (GL). The IGF1 locus genotype (microsatellite sequence) was found to affect (P≤0.01) the TNB, NBA and GL when based on analysis of sows with all litters born. No association between reproductive traits and ESR genotype was found in any restrictive site. However,interesting appeared the results of the analysis including an interaction between ESR genotypem in three polymorphic sites where almost all traits investigated appeared associated (P≤0.05) with ESR genotype. However, due to the limited number of animals, conclusions on the relationship between gene polymor-phisms and reproduction traits must be considered as preliminary, and thus treated with care.

PL

Na 53 lochach pokolenia F1 (knury złp × lochy wbp) badano polimorfizm genu insulino-podobnego czynnika wzrostu 1 (IGF1) i genu receptora estrogenu (ESR), określając jego wpływ na liczbę prosiąt urodzonych ogółem (TNB), liczbę prosiąt urodzonych żywo (NBA), masę miotu przy urodzeniu (LWB),masę miotu w dniu odsadzenia (LWW), liczbę odsadzonych prosiąt (NPW), średnią masę prosięcia przy odsadzeniu (AWW) i długość ciąży (GL). Stwierdzono istotną (P≤0.01) zależność między genotypem IGF1 (sekwencja mikrosatelitarna) a TNB,NBA i GL. Zależności takiej nie stwierdzono natomiast między genotypem ESR a badanymi cechami reprodukcyjnymi,w żadnym z analizowanych miejsc restrykcyjnych. Z drugiej strony, interesujące rezultaty uzyskano w wyniku statystycznej analizy dokonanej z uwzględnieniem interakcji między genotypami ESR w trzech miejscach polimorficznych, gdzie prawie wszystkie badane wskaźniki rozrodu okazały się istotnie zależne od genotypu. Ze względu jednak na niewielką liczbę zwierząt, wnioskowanie o zależności między polimorfizmami badanych genów a cechami reprodukcyjnymi jest jedynie wstępne i należy je traktować.

Słowa kluczowe

EN

DNA sequence; polymorphism; animal genetics; F1 sow; estrogen receptor; animal breeding; insulin-like growth factor 1; ESR gene; reproduction trait; IGF1 gene; sow

• Wydawca: -
• Czasopismo: Animal Science Papers and Reports
• Rocznik: 2004
• Tom: 22
• Numer: 2
• Opis fizyczny: p.215-226,fig.,ref.

Twórcy

autor

Korwin-Kossakowska A

• Polish Academy of Sciences, Jastrzebiec, 05-552 Wolka Kosowska, Poland

autor

Sender G.

autor

Kuryl J.

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