Effects of moderate physical training on blood pressure variability and hemodynamic pattern in mildly hypertensive subjects
The objective of our study was to compare the cardiovascular effects of moderate exercise training in heathy young (NTS, n=18, 22.9±0.44 years) and in hypertensive human subjects (HTS, n=30, 23±1.1). The VO2max did not significantly differ between groups. HTS of systolic blood pressure (SBP) 148±3.6 mmHg and diastolic blood pressure(DBP) 88±2.2mmHg, and NTS of SBP: 128.8 ± 4 mmHg and DBP: 72 ± 2.9 mmHg were submitted to moderate dynamic exercise training, at about 50% VO2max 3 times per week for one hour, over 3 months. VO2max was measured by Astrand's test. Arterial blood pressure was measured with Finapres technique, the stroke volume, cardiac output and arm blood flow were assessed by impedance reography. Variability of SBP and pulse interval values (PI) were estimated by computing the variance and power spectra according to FFT algorithm. After training period significant improvements in VO2max were observed in NTS- by 1.92 ±0.76 and in HTS by 3±0.68 ml/kg/min). In HTS significantly decreased: SBP by 19 ±2.9 mmHg, in DBP by 10.7±2 mmHg total peripheral resistance (TPR) by 0.28 ±0.05 TPR units. The pretraining value of low frequency component power spectra SBP (LFSBP) was significantly greater in HTS, compared to NTS. PI variance was lower in HTS, compared to NTS. After physical training, in HTS PI variance increased suggesting a decrease in frequency modulated sympathetic activity and increase in vagal modulation of heart rate in mild hypertension. A major finding of the study is the significant decrease of resting low frequency component SBP power spectrum after training in HTS. The value of LFSBP in trained hypertensive subjects normalized to the resting level of LFSBP in NTS. Our findings suggest that antihypertensive hemodynamic effects of moderate dynamic physical training are associated with readjustment of the autonomic cardiovascular control system.