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2005 | 46 | 4 |

Tytuł artykułu

No incidence of DUMPS arriers in Polish dairy cattle

Warianty tytułu

Języki publikacji

EN

Abstrakty

EN
DUMPS (Deficiency of Uridine Monophosphate Synthase) is a hereditary recessive disorder in Holstein cattle causing early embryo mortality during its implantation in the uterus. The only way to avoid the economic losses is early detection of DUMPS carriers. Because American Holstein semen has been intensively imported to Poland since 1970, there was a risk that DUMPS could have spread in Polish dairy cattle. In our study, 2209 dairy cattle of the Polish Holstein breed have been screened by the DNA test. The dominant group was young bulls entering the testing program (1171) and proven bulls (781). They represented all sires entering Polish breeding programs between 1999 and 2003. Also, 257 sire dams were included in the screening program. No DUMPS carrier has been found. Our results then indicate that the population of dairy cattle reared in Poland is free from DUMPS. Because of the economical significance of the DUMPS mutation and its recessive mode of inheritance, attention has to be paid to any case of a bull having in his origin any known DUMPS carrier. Such a bull should be tested and if positive eliminated from the active population. Also, young bulls (testing bulls) should be screened for DUMPS if in their progeny a high incidence of embryo mortality is observed and their genealogy cannot exclude their relatedness to any DUMPS carriers.

Słowa kluczowe

Wydawca

-

Rocznik

Tom

46

Numer

4

Opis fizyczny

p.395-397,fig.,ref.

Twórcy

autor
  • University of Warmia and Mazury in Olsztyn, M.Oczapowskiego 5, 10-957 Olsztyn, Poland
autor
autor

Bibliografia

  • Robinson JL, Drabik MR, Dombrowski DB, Clark JH, 1983. Consequences of UMP synthase deficiency in cattle. Proc Nat Acad Sci USA 80: 321-323.
  • Robinson JL, Popp RG, Shanks RD, Oosterhof A, Veerkamp JH, 1993. Testing for deficiency of uridine monophosphate synthase among Holstein Friesian cattle of North America and Europe. Livest Prod Sci 36: 287-298.
  • Schwenger B, Tammen I, Aurich C, 1994. Detection of homozygous recessive genotype for deficiency of uridine monophosphate synthase by DNA typing among bovine embryos produced in vitro. J Reprod Fertil 100: 511-514.
  • Shanks RD, 1990. Reproductive consequences of deficiency of uridine monophosphate synthase in Holstein cattle. Am Vet Res 51: 800-802.
  • Shanks RD, Bragg DSA, Robinson JL, 1987. Deficiency of uridine monophosphate synthase in Holstein cattle: inheritance and body measurements. J Anim Sci 64: 695-700.
  • Shanks RD, Robinson J, 1990. Deficiency of uridine monophosphate synthase among Holstein cattle. C Vet 80: 119-122.
  • Schoeber S, Simon D, Schwenger B, 1993. Sequence of the cDNA encoding bovine uridine monophosphate synthase. Gene 124: 307-308.

Typ dokumentu

Bibliografia

Identyfikatory

Identyfikator YADDA

bwmeta1.element.agro-article-cf5cd195-0e2a-4611-b19c-dc5718e16719
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