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2001 | 48 | 1 |

Tytuł artykułu

Structure and functions of 5S rRNA

Warianty tytułu

Języki publikacji

EN

Abstrakty

EN
The ribosome is a macromolecular assembly that is responsible for protein biosynthesis in all organisms. It is composed of two-subunit, ribonucleoprotein particles that translate the genetic material into an encoded polypeptides. The small subunit is the site of codon-anticodon interaction between the messenger RNA (mRNA) and transfer RNA (tRNA) substrates, and the large subunit catalyses peptide bond formation. The peptidyl- transferase activity is fulfilled by 23S rRNA, which means that ribosome is a ribozyme. 5S rRNA is a conserved component of the large ribosomal subunit that is thought to enhance protein synthesis by stabilizing ribosome structure. This paper shortly summarises new results obtained on the structure and function of 5S rRNA.

Wydawca

-

Rocznik

Tom

48

Numer

1

Opis fizyczny

p.191-198,fig.

Twórcy

  • Polish Academy of Sciences, Z.Noskowskiego 12, 61-704 Poznan, Poland
autor
autor

Bibliografia

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  • 11.Gabashvili, I.S., Agrawal, R.K., Spahn, Ch.M.T., Grassucci, R.A., Svergun, D.I., Frank, J. & Penczek, P. (2000) Solution structure of the E. coli 70S ribosome at 11.5 A resolution. Cell 100, 537-549.
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  • 14.Nissen, P., Hansen, J., Ban, N., Moore, P.B. & Steitz, T.A. (2000) The structural basis of ribosome activity in peptide bond synthesis. Science 289, 920-930.
  • 15.Szymanski, M., Barciszewska, M., Barciszewski, J. & Erdmann, V.A. (2000) 5S ribosomal RNA database Y2K. Nucleic Acids Res. 28, 166-167.
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  • 20.Sergiev, P.V., Bogdanov, A.A., Dahlberg, A.E. & Dontsova, O. (2000) Mutations at position A960 of E. coli 23 S ribosomal RNA influence the structure of 5 S ribosomal RNA and the peptidyltransferase region of 23 S ribosomal RNA. J. Mol. Biol. 299, 379-389.
  • 21.Khaitovich, P. & Mankin, A.S. (2000) Effect of antibiotics on large ribosomal subunit assembly reveals possible function of 5S rRNA. J. Mol. Biol. 291, 1025-1034.
  • 22.Lorenz, S., Perbandt, M., Lippmann, C., Moore, K., DeLucas, L.J., Betzel, C. & Erdmann, V.A. (2000)Crystallization of engineered Thermus flavus 5S rRNA under earth and microgravity conditions. Acta Crystallogr. D. Biol. Crystallogr. 56, 498-500.
  • 23.Bloemink, M.J. & Moore, P.B. (1999) Phosphorylation of ribosomal protein L18 is required for its folding and binding to 5S rRNA. Biochemistry 38, 13385-13390.
  • 24.Claussen, M., Rudt, F. & Pieler, T. (1999) Functional modules in ribosomal protein L5 for ribonucleoprotein complex formation and nucleocytoplasmic transport. J. Biol. Chem. 274, 33951-33958.
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  • 26.Park, J.W. & Bae, Y.S. (1999) Phosphorylation of ribosomal protein L5 by protein kinase CKII decreases its 5S rRNA binding activity. Biochem. Biophys. Res. Commun. 263, 475-481.
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  • 28.Lu, M. & Steitz, T.A. (2000) Structure of Escherichia coli ribosomal protein L25 complexed with a 5S rRNA fragment at 1.8 A resolution. Proc. Natl. Acad. Sci. U.S.A. 97, 2023-2028.
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  • 33.Conconi, A., Liu, X., Koriazova, L., Ackerman, E.J. & Smerdon, M.J. (1999) Tight correlation between inhibition of DNA repair in vitro and transcription factor IIIA binding in 5S ribosomal RNA gene. EMBO J. 18, 1387-1396.
  • 34.Liu, X., Mann, D.B., Suquet, C., Springer, D.L. & Smerdon, M.J. (2000) Ultraviolet damage and nucleosome folding of the 5S ribosomal RNA gene. Biochemistry 39, 557-566.
  • 35.Liu, X. & Smerdon, M.J. (2000) Nucleotide excision repair of the 5 S ribosomal RNA gene assembled into a nucleosome. J. Biol. Chem. 275, 23729-23735.
  • 36.Vitolo, J.M., Thiriet, C. & Hayes, J.J. (2000) The H3-H4 N-terminal tail domains are the primary mediators of transcription factor IIIA access to 5S DNA within a nucleosome. Mol. Cell. Biol. 20, 2167-2175.
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Typ dokumentu

Bibliografia

Identyfikatory

Identyfikator YADDA

bwmeta1.element.agro-article-ceaaaf96-368f-45a2-aaf5-816066c48ecd
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