Infiltrative form of a tumour in cardiac base in a dog with dilated cardiomyopathy: clinical and morphological correlations. A case report

• Autorzy: Nowak M , Noszczyk-Nowak A. , Mroz K. , Dziegiel P.
• Języki publikacji: EN

Abstrakty

EN

The case of a 12-year-old boxer dog, with an infiltrating tumour in cardiac base and dilated cardiomyopathy was described. Morphological and biochemical examinations of the blood, ECG, and USG of the heart were performed. In the resting ECG record, atrial fibrillation was detected with rapid action of ventricles. Echocardiography demonstrated distension of all cardiac cavities and a decreased contractility of the left ventricular myocardium. Despite intense treatment, the condition of the dog deteriorated: anaemia and renal insufficiency appeared and asphyxia intensified. At the owners' request, the dog was subjected to euthanasia. On autopsy, a tumour in the cardiac base was detected, which infiltrated the left atrial wall. Histopathology and immunohistochemistry permitted to diagnose neoplastic hypertrophy of chemodectoma type.

Słowa kluczowe

EN

histopathology; cardiac base; immunohistochemistry; clinical examination; veterinary medicine; chemodectoma type; morphological examination; animal disease; dilated cardiomyopathy; dog

• Wydawca: -
• Czasopismo: Bulletin of the Veterinary Institute in Puławy
• Rocznik: 2008
• Tom: 52
• Numer: 3
• Opis fizyczny: p.485-490,fig.,ref.

Twórcy

autor

Nowak M

• Wroclaw University of Environmental and Life Sciences, 50-375 Wroclaw, Poland

autor

Noszczyk-Nowak A.

autor

Mroz K.

autor

Dziegiel P.

Bibliografia

• 1. Aresu L., Tursi M., Iussich S., Guarda F., Valenza F.: Use of S-100 and chromogranin antibodies as immunohistochemical markers on detection of malignancy in aortic body tumors in dog. J Vet Med Sci 2006, 11, 1229-1233.
• 2. Aupperle H., März I., Ellenberger C., Buschatz S., Reischauer A., Schoon H.A.: Primary and secondary heart tumours in dogs and cats. J Comp Pathol 2007, 136, 18-26.
• 3. Brown P., Rema A., Gather F.: Immunohistochemical characteristics of canine aortic and carotid body tumors. J Am Vet Med Assoc 1997, 211, 736-740.
• 4. Cho K., Park N., Park I., Kang B., Onuma M.: Metastatic intracavitary cardiac aortic body tumor in a dog. J Vet Med Sci 1998, 60, 1251-1253.
• 5. Dean M.J., Strafuss A.C.: Carotid body tumors in the dog: A review and report of four cases. J Am Vet Med Assoc 1975, 166, 1003-1006.
• 6. Degorce F.: Assessment of chromogranin A using two- site immunoassay. Selection of a monoclonal antibody pair unaffected by human chromogranin A processing. Adv Exp Med Biol 2000, 482, 339-350.
• 7. Gliatto J., Crawford M., Snider T., Pechman R.: Multiple organ metestasis of an aortic body tumor in a boxer. J Am Vet Med Assoc 1987, 191, 1110-1112.
• 8. Iana A., Silverberg D.S., Wexler D.: Therapy insight: congestive heart failure, chronic kidney disease and anemia, the cardio-renal-anemia syndrome. Nat Clin Pract Cardiovasc Med 2005, 2, 95-100.
• 9. Johnson K.H.: Aortic body tumors in the dog. J Am Vet Med Assoc 1968, 152, 154-160.
• 10. Jubb K.F., Kennedy P.C.: Tumors of the nonchromaffin paraganglia in dogs. Cancer 1957, 10, 89-99.
• 11. Kerstetter K., Krahwinkel D., Millis D., Hahn K.: Pericardiotomy in dogs: 22 cases (1978-1994). J Am Vet Med Assoc 1997, 211, 736-740.
• 12. Levin A.: Anemia and left ventricular hypertrophy in chronic kidney disease populations: a review of the current state of knowledge. Kidney Int Suppl 2002, 61, 35-38.
• 13. Lloyd R.V., Cano M., Rosa P., Hille A., Huttner W.B.: Distribution of chromogranin A and secretogranin I (chromogranin B) in neuroendocrine cells and tumors. Am J Pathol 1988, 130, 296-304.
• 14. Meuten D.J.: Tumors in Domestic Animals, Iowa State Press, Iowa 2002, pp. 691-695.
• 15. Naude S., Miller D.: Magnetic resonance imaging findings of metestatic chemodectoma in a dog. J S Afr Vet Assoc 2006, 77, 155-159.
• 16. Nillson A.: A case of metastasising tumour of the glomus aorticus in a dog. Nord Vet Med 1956, 8, 875- 881.
• 17. Nowak M., Noszczyk-Nowak A., Sławuta P., Nowaczyk R., Polańska J.: Metastasis of mammary carcinoma to myocardium in dog: clinical and morphological correlation. Bull Vet Inst Pulawy 2007, 51, 313-319.
• 18. Paltrinieri S., Sartorelli P., De Vecchi B., Agnes F.: Metabolic findings in the erythrocytes of cardiopathic and anaemic dogs. J Comp Pathol 1998, 118, 123-133.
• 19. Perez C.A., Brady L.W.: Unusual non-epithelial tumors of the head and neck. In: Principles and Practice of Radiation Oncology. Perez C.A. Lippincott Williams and Wilkins, New York, 2004, pp. 1117-1123.
• 20. Portela-Gomes G.M.: Chromogranin A immunoreactivity in neuroendocrine cells in the human gastrointestinal tract and pancreas. Adv Exp Med Biol 2000, 482, 193- 203.
• 21. Priester W., Goodman D., Theilen G.: Nine simultaneous primary tumors in a Boxer dog. J Am Vet Med Asscoc 1977, 170, 823-826.
• 22. Robbins S.L., Cotran R.S., Kumar V.: Robbins Patologia, Elsevier Urban & Partner, Wrocław, 2007, pp. 452-453.
• 23. Sander C.H., Whitenack D.I.: Canine malignant carotid body tumor. J Am Vet Med Assoc 1970, 156, 606-610.
• 24. Sapieżyński R.: Nowotwory śródpiersia u psów i kotów. Część I. Nowotwory serca. Życie wet. 2008, 83, 20-23.
• 25. Silverberg D.S., Wexler D., Bloom M., Wollman Y., Iana A.: The cardio-renal anemia syndrome: does it exist? Nephrol Dial Transplant 2003, 18, 7-12.
• 26. Silverberg D.S., Wexler D., Iana A., Schwarz D.: The interaction between heart failure and other diseases, renal failure, and anemia. Semin Nephrol 2006, 26, 296-306.
• 27. Ware W.A., Hopper D.L.: Cardiac tumors in dogs: 1982- 1995. J Vet Intern Med 1999, 13, 95-103.
• 28. Yates W.D., Lester S.J., Mills J.H.: Chemoreceptor tumors diagnosed at Western College of Veterinary Medicine 1967-1979. Can Vet J 1980, 21, 124-129.