A paradigm for quantifying ventricular contraction

• Autorzy: Palladino J L , Noordergraaf A.
• Języki publikacji: EN

Abstrakty

EN

The left ventricle may be described as a time, volume and flow dependent pressure generator. First, isovolumic pressure is measured at various end-diastolic volumes. Next, pressure is adjusted to account for small changes accompanying ejection, denoted the ejection effect. The resulting analytical function can describe pressure generation and ventricular outflow of the ventricle under a wide range of contractile and vascular conditions. This paradigm is unique in separating isovolumic from ejecting ventricular properties, as well as ventricular from vascular conditions.

Słowa kluczowe

EN

arterial load; contractile condition; vascular condition; disease state; normal state; heart function; ventricular contraction

• Wydawca: -
• Czasopismo: Cellular and Molecular Biology Letters
• Rocznik: 2002
• Tom: 07
• Numer: 2
• Opis fizyczny: p.331-335,fig.

Twórcy

autor

Palladino J L

• Trinity College, Hartford, CT, USA

autor

Noordergraaf A.

Bibliografia

• 1. Palladino, J. L., Mulier, J. P. and Noordergraaf, A. Defining ventricular elastance. Proc. 20th Int. Conf. IEEE Eng. Med. Biol. Soc. (1998) Hong Kong, 383-386.
• 2. Palladino, J. L., Rabbany, S. Y., Mulier, J. P. and Noordergraaf, A. A perspective on myocardial contractility. Tech. Health Care 5 (1997) 135-144.
• 3. Danielsen, M. Modeling of Feedback Mechanisms which Control the Heart Function.. PhD diss., Roskilde University, Denmark, 1998.
• 4. Palladino, J. L., Mulier, J. P., and Noordergraaf, A. Closed-loop circulation model based on the Frank mechanism. Surv. Math. Ind. 7 (1997) 177-186.