Paralityczne toksyny morskie jako zagrozenie dla zdrowia konsumenta

• Autorzy: Michalski M

Warianty tytułu

EN

Paralytic shellfish poisoning as a health risk

• Języki publikacji: PL

Abstrakty

EN

Shellfish poisoning is caused by a group of toxins elaborated by planktonic algae (dinoflagellates), in most cases upon which the shellfish feed. The main groups of biotoxins harmful for human beings are: DSP, NSP, ASP and PSP. The most frequent and dangerous for our lives is paralytic shellfish poisoning (PSP). In the case of PSP, the effects are predominantly neurological and include tingling, burning, numbness, drowsiness, incoherent speech, and respiratory paralysis. The 20 toxins responsible for paralytic shellfish poisoning are all derivatives of the saxitoxin group. Saxitoxin is heat-stable and unaffected by standard cooking or steaming; it is water-soluble, and can be concentrated in broth. To prevent outbreaks of PSP and other shellfish intoxications, samples of susceptible mollusks are periodically collected in the coastal states and tested for toxin by mouse bioassay. When toxin levels exceed 80 µg/100 g, affected growing areas are quarantined, and sale of shellfish is prohibited. Modern chemical techniques, for instance immunoassay, phosphatase test or chromatography (HPLC, LC-MS), are quite suitable for the detection of PSP.

Słowa kluczowe

PL

zagrozenia zdrowia; zywnosc pochodzenia morskiego; biotoksyny; saksytoksyna; biotoksyny morskie; metody; wykrywanie; toksyna paralityczna

• Wydawca: -
• Czasopismo: Medycyna Weterynaryjna
• Rocznik: 2007
• Tom: 63
• Numer: 12
• Opis fizyczny: s.1530-1533,bibliogr.

Twórcy

autor

Michalski M

• Panstwowy Instytut Weterynaryjny - Panstwowy Instytut Badawczy, Al.Partyzantow 57, 24-100 Pulawy

Bibliografia

• 1.Amorim A., Dale B.: Distribution of cysts from toxic or potentially toxic dinofla-gellates along the Portuguese coast, [w:] Reguera B., Blanco J., Fernandez M., Wyatt T.: Harmful Algae, Proc. VIII Internat. Conf. Harmful Algae, June 1997,Vigo, Spain, s. 64-65.
• 2.Anderson D. M.: Red tides. Scientific American 1994, 271, 62-68.
• 3.Andrinolo D., Michea L. F., Lagos N.: Toxic effects, pharmacokinetics and clearance of saxitoxin, a component of paralytic shellfish poison (PSP) in cats. Toxicon 1999, 37, 447-464.
• 4.Anon.: IPCS. International Programme on Chemical Safety. Aquatic (Marine and Freshwater) Biotoxins. Environmental Health Criteria 37. WHO, Rome 1984.
• 5.Bower D. J., Hart R. J., Matthews P. A., Howden M. E. H.: Nonprotein neurotoxins. Clin. Toxicol. 1981, 18, 813-843.
• 6.Cembela A. D., Lamoreux G.: Rev. Int. Oceanogr. Med. 1991, [w:] Egmond H. P. Van: Paralytic and diarrhoeic shellfish poisons: occurrence in Europe, toxicity, analysis and regulation. J. Nat. Toxins 1993, 2, 41-83.
• 7.Chu F. S., Hsu K. H., Huang X., Barrett R., Allison C.: Screening of paralytic shell fish poisoning toxins in naturally occurring samples with three different direct competitive enzyme-linked immunosorbent assays. J. Agric. Food Chem. 1996, 44, 4034-4047.
• 8.Earnshaw A.: Marine toxins, pilot study. Report Food Analysis Performance Assessment Scheme, Central Science Laboratory, Sand Hutton, York, UK 2003.
• 9.Egmond H. P.Van, Mouriño A., Burdaspal P. A., Bustos J., Legarda T., Mesego A., Paulsch W. E., Saldago C., Van de Top H. J., Boenke A.. The certification of the mass fractions of saxitoxin and dc-saxitoxin in two mussel reference materials (CRM 542 & 543) including the identification of other PSP toxins, and a spiking procedure based on an enrichment solution (CRM 663) with a certified mass concentration of saxitoxin. Publication of the European Communities. Directorate-General Science, Research and Development, 1998. Report EUR Report 18318.
• 10.Egmond H. P.Van., Speijers G. J. A.: Natural Toxins II. Phycotoxins, [w:] Van der Heijden K. i in.: International Food Safety Handbook. Science, International Regulation and Control. Marcel Dekker Inc. New York 1999, 357-368.
• 11.Garthwaite I., Ross K. M., Miles C. O. Briggs L. R., Towers N. R., Borrell T., Busby P.: Integrated enzyme-linked immunosorbent assay screening system for amnesic, neurotoxic, diarrhetic, and paralytic shellfish poisoning toxins found in New Zealand. J. AOAC Int. 2001, 84, 1643-1648.
• 12.Gessner B. D., Bell P., Doucette G. J., Moczydlowski E., Poli M. A., Van Dolah F., Hall S.: Hypertension and identification of toxin in human urine and serum following a cluster of mussel-associated paralytic shellfish poisoning outbreaks. Toxicon 1997, 35, 711-722.
• 13.Hallegraeff G. M., Anderson D. M., Cembella A. D.: Manual on Harmful Marine Microalgae. IOC Manuals and Guides No. 33., UNESCO, Rzym 1995.
• 14.Hollingworth T., Wekell M. M.: Fish and other Marine Products. 959.08. Paralytic shellfish poisoning. Biological Method, Final Action, [w:] Hellrich K.: Official Methods of Analysis of the Association of Official Analytical Chemists, Arlington, Virginia, USA 1990, 881-882.
• 15.Ikawa M., Van Egmond H. P.: Paralytic and diarrhoeic shellfish poisons: occurrence in Europe, toxicity, analysis and regulation. J. Nat. Toxins 1985, 1, 41-83.
• 16.Kasuga F., HaraKudo Y., Machii K.: Evaluation of enzyme-linked imunosorbent assay (ELISA) kit for paralytic shellfish poisoning toxins. J. Food Hyg. Soc. Japan 1996, 37, 407-410.
• 17.Kawatsu K., Hamano Y., Sugiyama A., Hashizume K., Noguchi T.: Development and application of an enzyme immunoassay based on a monoclonal antibody against gonyautoxin components of paralytic shellfish poisoning toxins. J. Food Prot. 2002, 65, 1304-1308.
• 18.Lagos N.: Microalgal blooms: A global issue with negative impact in Chile. Biol. Res. 1998, 31, 375-386.
• 19.LeDoux M., Hall S.: Proficiency testing of eight French laboratories in using the AOAC mouse bioassay for paralytic shellfish poisoning: interlaboratory collaborative study. Food Chem. Contam. 2000, 83, 305-310.
• 20.Lindahl O.: Occurrence and monitoring of harmful algae in the marine environment. Proc. of the IX International IUPAC Symposium on Mycotoxins and Phycotoxins. Fort Collins, Colorado 1998, s. 409-423.
• 21.MacKenzie L., Berkett N.: Cell morphology and PSP-toxin profiles of Alexandrium minutum in the Marlborough Sounds, New Zealand. New Zealand J. Mar. Freshwater Res. 1997, 31, 403-409.
• 22.Michalski M. M.: Biotoksyny morskie występowanie i metody analizy. ¯ywnoœæ. Nauka. Technologia. Jakoœæ 2006, 3 (13), 16-22.
• 23.Mons M. N., Van Egmond H. P., Speijers G. J. A.: Paralytic shellfish poisoning: A review. RIVM Report 388802 005, June 1998.
• 24.Oikawa H., Fujita T., Satomi M., Suzuki T., Kotani Y., Yano Y.: Accumulation of paralytic shellfish poisoning toxins in the edible shore crab Telmessus acutidens. Toxicon. 2002, 40, 1593-1599.
• 25.Onoue Y., Tamao N., Maruyama J., Hashimoto K., Seto H.: Properties of two toxins newly isolated from oysters. J. Agric. Food Chem. 1983, 31, 420-423.
• 26.Pleasance S., Ayer S. W., Laycock M. V., Thibault P.: Ionspray mass spectrometry of marine toxins. III. Analysis of paralytic shellfish poisoning toxins by flow-injection analysis, liquid chromatography/mass spectrometry and capillary electrophoresis/mass spectrometry. Rapid Commun. Mass Spectrom. 1992, 6, 14-24.
• 27.Quilliam M. A., Janecek M., Lawrence J. F.: Characterization of the oxidation products of paralytic shellfish poisoning toxins by liquid chromatography/mass spectrometry. Rapid Commun. Mass Spectrom. 1993, 6, 14-24.
• 28.Quilliam M., Hess P., Dell’Aversano C.: Recent developments in the analysis of phycotoxins by liquid chromatography-mass spectrometry, [w:] DeKoe W. J., Samson R. A., Van Egmond H. P., Gilbert J., Sabino M.: Mycotoxins and phycotoxins in perspective at the turn of the century. Wageningen, Netherlands, Ponsen&Looyen 2001, 383-391.
• 29.Sullivan J. J.: Methods of analysis for DSP and PSP toxins in shellfish: a review. J. Shellfish Res. 1988, 7, 587-595.
• 30.Thibault P., Pleasance S., Laycock M. V.: Analysis of paralytic shellfish poisons by capillary electrophoresis. J. Chromatogr. 1991, 542, 483-501.
• 31.Top H. J. Van den, Boenke A., Burdaspal P. A.: The development of reference materials for paralytic shellfish poisoning toxins in lyophilized material. II: Certification study. Food Add. Contam. 2001, 18, 810-824.
• 32.Top H. J. Van den, Boenke A., Burdaspal P. A., Bustos J., Van Egmond H. P., Legarda T., Mesego A., Mourino A., Paulsch W. E., Salgado C.: The development of reference materials for paralytic shellfish poisoning toxins in lyophilized mussel. I: Interlaboratory studies of methods of analysis. Food Add. Contam. 2000, 17, 419-433.
• 33.Wright J. L. C., Boyd R. K., De Freitas A. S. W., Falk M., Foxall R. A., Jamieson W. D., Laycock M. V., McCulloch A. W., McInnes A. G., Odens P., Pathak V. P., Quilliam M. A., Ragan M. A., Sim P. G., Thibault P., Walter J. A., Gilgan M., Richard D. J., Dewar D.: Identification of domoic acid, a neuroexcitatory amino acid, in toxic mussels from eastern Prince Edward Island. Can. J. Chem. 1989, 67, 481-490.