The plant Nudix hydrolase family

• Autorzy: Kraszewska E.
• Języki publikacji: EN

Abstrakty

EN

Nudix hydrolases are a family of proteins defined by a conserved amino-acid sequence GX5-EX7REUXEEXGU, where U is a hydrophobic residue. These enzymes are widely distributed among all classes of organisms and catalyze, with varying degrees of substrate specificity, the hydrolysis of a variety of nucleoside diphosphate derivatives: nucleoside di- and triphosphates and their oxidized forms, dinucleoside polyphosphates, nucleotide sugars, NADH, coenzyme A and the mRNA cap. Nudix proteins are postulated to control the cellular concentration of these compounds. The genome of the model plant Arabidopsis thalianacontains 29 genes coding for putative Nudix hydrolases. Recently, several Arabidopsis Nudix genes have been cloned and their products characterized. This review summarizes current knowledge on these plant enzymes and discusses their possible cellular functions.

Słowa kluczowe

PL

protein; Nudix hydrolase family; enzyme; pyrophosphohydrolase; plant; Arabidopsis thaliana; amino acid sequence; Nudix gene; cloning; plant enzyme; cellular function; genome model; Nudix protein

• Wydawca: -
• Czasopismo: Acta Biochimica Polonica
• Rocznik: 2008
• Tom: 55
• Numer: 4
• Opis fizyczny: p.663-671,ref.

Twórcy

autor

Kraszewska E.

• Polish Academy of Sciences, Pawinskiego 5A, 02-106 Warsaw, Poland

Bibliografia

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