The influence of ethanol on tissue distribution and the toxic effects of lead on rats

• Autorzy: Kulikowska E. , Moniuszko-Jakoniuk J. , Jablonska E. , Kaluzynski A.
• Języki publikacji: EN

Abstrakty

EN

The aim of this study was to elucidate the influence of ethanol on concentrations of lead in tissues of rats exposed to lead acetate. The experiment was made on Wistar rats. The animals were given lead acetate (500 mg 1-1 of lead) in drinking water for 6 weeks. For 4 to 5 days before the end of exposure to lead, the animals were given intragastrically 25% solution of ethanol in doses of 5 g/kg body weight, every 12 hours. After exposure to lead acetate an increased level of lead was found in all examined tissues, i.e. blood, liver, kidneys, spleen, bones. Ethanol applied together with lead caused a redistribution of lead from bones and liver to blood and kidneys.

Słowa kluczowe

EN

ethanol; toxic effect; accumulation; lead; distribution; rat; tissue

• Wydawca: -
• Czasopismo: Polish Journal of Environmental Studies
• Rocznik: 1995
• Tom: 04
• Numer: 4
• Opis fizyczny: p.51-54,ref.

Twórcy

autor

Kulikowska E.

• Medical Academy, Mickiewicza 2c, 15-222 Bialystok, Poland

autor

Moniuszko-Jakoniuk J.

autor

Jablonska E.

autor

Kaluzynski A.