Cyclin-dependent protein kinase-2 regulation by phosphorylation, a molecular dynamics study

• Autorzy: Bartova I , Otyepka M. , Kriz Z. , Koca J.
• Języki publikacji: EN

Słowa kluczowe

EN

cell cycle; eukaryotic cell; phosphorylation; enzyme; regulation; cyclin-dependent protein kinase 2; molecular dynamics

• Wydawca: -
• Czasopismo: Cellular and Molecular Biology Letters
• Rocznik: 2003
• Tom: 08
• Numer: 2A
• Opis fizyczny: p.574-575,fig.

Twórcy

autor

Bartova I

• Masaryk University, Kotlarska 2, 611 37 Brno, Czech Republic

autor

Otyepka M.

autor

Kriz Z.

autor

Koca J.

Bibliografia

• 1. Morgan, D.O. Cyclin-dependent kinases: engines, clocks and microprocessors. Annu. Rev. Cell Dev. Biol. 13 (1997) 261-291.
• 2. Jeffrey, P.D., Russo, A.A, Polyak, K., Gibbs, E., Hurwitz, J., Massague, J. and Pavletich, N.P. Mechanism of CDK activation revealed by the structure of a cyclinA-CDK2 complex. Nature 376 (1995) 313-320.
• 3. Otyepka, M., Kříž, Z. and Koča, J. Dynamics and binding modes of free cdk2 and its two complexes with inhibitors studied by computer simulations. J. Biol. Struct. Dyn. 20 (2002) 141-154.
• 4. De Bondt, H.L., Rosenblatt, J., Jancarik, J., Jones, H.D., Morgan, D.O. and Kim, S.H. Crystal structure of cyclin-dependent kinase 2. Nature 363 (1993) 595-602.
• 5. Case, D.A., Pearlman, D.A., Caldwell, J.W., Cheatham III., T.E., Ross, W.S., Simmerling, C.L., Darden, T.A., Merz, K.M., Stanton, R.V., Cheng, A.L., Vincent, J.J., Crowley, M., Tsui, V., Radmer, R.J., Duan, Y., Pitera, J., Massova, I., Seibel, G.L., Singh, U.C., Weiner, P.K. and Kollman, P.A. AMBER ver. 6.0, University of California, San Francisco, (1999).