The effect of extracellular substance components on the proliferation and expression of hormones in cultured cells of medullary thyroid carcinomas

• Autorzy: Zabel M , Gebarowska E. , Surdyk-Zasada J. , Lesisz I. , Kasprzak A. , Seidel J.
• Języki publikacji: EN

Abstrakty

EN

The effects were examined of selected extracellular medium (ECM) components on the proliferation of medullary thyroid carcinoma cells and on the production of calcitonin and CGRP. Human TT cells and rat rMTC cells were cultured for 24, 48 and 72 hours on glass coated with type I collagen, fibronectin or poly-D-lysine. More pronounced proliferation was demonstrated by TT cells grown on poly-Dlysine or collagen in comparison with the control and less pronounced proliferation was typical of cells grown on fibronectin. On the other hand, rMTC cells were more markedly manifest on any ECM substrates than that on glass. Alterations in the proliferation were paralleled by changes in the expression of CT and CGRP.

Słowa kluczowe

EN

calcitonin; extracellular substance; TT cell; proliferation; carcinoma; rMTC cell; extracellular matrix; cultured cell; medullary thyroid carcinoma; expression; cell culture; hormone

• Wydawca: -
• Czasopismo: Folia Morphologica
• Rocznik: 2004
• Tom: 63
• Numer: 1
• Opis fizyczny: p.63-66,fig.,ref.

Twórcy

autor

Zabel M

• University School of Medicine, Chalubinskiego 6a, 50-368 Wroclaw, Poland

autor

Gebarowska E.

autor

Surdyk-Zasada J.

autor

Lesisz I.

autor

Kasprzak A.

autor

Seidel J.

Bibliografia

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