Evaluation of the possibility of horizontal gene transfer and accumulation of transgenic DNA from the diet in the bodies of rats

• Autorzy: Kosieradzka I. , Vasko V. , Szwacka M. , Przybysz A. , Fiedorowicz S.
• Języki publikacji: EN

Abstrakty

EN

The procedures for GMO safety tests include traceability of transgenic protein and transgenic DNA if the plant constitutes a component in the diet for an animal. This is due to the possibility of horizontal transfer of genes, accumulation of transgenic DNA in consumer’s organs, or induction of antibiotic resistance in gastrointestinal tract microflora. The last possibility is related to the use of marker genes in the process of transformation. In an in vivo experiment conducted on laboratory rats with the use of transgenic cucumbers expressing the pre-prothaumatin gene, the presence of transgenic DNA in the tissue of kidneys and liver was not detected. Resistance to neomycin of gastrointestinal tract microflora of the rats fed the GMO diet was not found, despite the use of marker genes (npt II) in the process of transformation of the investigated plants.

Słowa kluczowe

PL

rat; in vivo experiment; diet; body; transgenic DNA; gene transfer; accumulation; horizontal gene transfer; possibility; cucumber; antibiotic resistance; plant constituent; animal feeding

• Wydawca: -
• Czasopismo: Journal of Animal and Feed Sciences
• Rocznik: 2010
• Tom: 19
• Numer: 2
• Opis fizyczny: p.307-315,fig.,ref.

Twórcy

autor

Kosieradzka I.

• Warsaw University of Life Sciences, Ciszewskiego 8, 02-786 Warsaw, Poland

autor

Vasko V.

autor

Szwacka M.

autor

Przybysz A.

autor

Fiedorowicz S.

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