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2007 | 51 | 2 |

Tytuł artykułu

Caudal extradural analgesia with lidocaine, xylazine, and a combination of lidocaine and xylazine in the Iranian river buffalo

Warianty tytułu

Języki publikacji

EN

Abstrakty

EN
This study was conducted to compare the time of onset, duration of action, and the extent of analgesia produced by a lidocaine/xylazine combination with those produced by lidocaine and xylazine alone after injection into the caudal extradural space of the Iranian river buffalo. The study was designed as a prospective, descriptive, observer-blind trial, in a Latin square pattern. Eleven adult (aged over 2 years) non- gravid and healthy females of Iranian river buffaloes (Bubalus bubalis), weighing from 450 to 650 kg, were used. Caudal extradural analgesia was achieved on 3 occasions at 14 d intervals by injection of 2% lidocaine (L; 0.22 mg kg⁻¹), 2% xylazine (X; 0.05 mg kg⁻¹), and a combination of 2% lidocaine(0.22 mg kg⁻¹) / 2% xylazine (LX; 0.05 mg kg⁻¹) in a Latin square design. Analgesia was determined by the lack of response to pinprick and haemostat pressure in the skin of the caudal areas. X was significantly longer (5.5 ± 0.7 min) than that by L or LX. Duration of analgesia was significantly longer by LX (172.3 ± 17.7 min) than that by either drug used alone (lidocaine, 79.5 ± 5.7 min; xylazine, 136.4±11.4 min). In X and LX groups, the level of analgesia ascended to thoracic segments; however, in lidocaine-treated buffaloes thighs, flank, and udders remained sensitive. In all the buffaloes, xylazine, administered either alone or with lidocaine, induced mild to moderate ataxia. It was concluded that the LX combination provided a more rapid onset and a longer duration of analgesia, and a more cranial spread of analgesic effect compared with either drug alone. As a result, the LX combination may offer a fast and long lasting anaesthesia/analgesia to perform obstetrical and surgical procedures without the need for re-injection.

Wydawca

-

Rocznik

Tom

51

Numer

2

Opis fizyczny

p.285-288,fig.,ref.

Twórcy

autor
  • Urmia University, 1177 Urmia, Iran
autor

Bibliografia

  • 1. Adetunji A., Ajadi R.A., Opia R.E.: A comparison of epidural anaesthesia with xylazine, bupivacaine and bupivacaine/xylazine mixture in West African Dwarf goats. Isr J Vet Med 2002, 57, 104-109.
  • 2. Aminkov B., Zlateva N.: Epidural anaesthesia for castration of the bitch. Bulg J Vet Med 2004, 7, 113-119.
  • 3. Bedder M.D., Kozody R., Palahniuk R.J.: Clonidine prolongs canine tetracaine spinal anesthesia. Can Anesth Soc J 1986, 33, 591-596.
  • 4. Caron J.P., LeBlanc P.H.: Caudal epidural analgesia in cattle using xylazine. Can J Vet Res 1989, 53, 486-489.
  • 5. Caulkett N.A., MacDonald D.G., Janzen E.D.: Xylazine hydrochloride epidural analgesia: a method of providing sedation and analgesia to facilitate castration of mature bulls. Comp Cont Edu Pract Vet 1993, 15, 1155-1159.
  • 6. Eisenbach J.C., DeKock M., Klimscha W.: Alpha 2- adrenergic agonists for regional anesthesia: a clinical review of clonidine (1984-85). Anaesthesiology 1996, 85, 655-674.
  • 7. Grubb T.L., Riebold T.W., Huber M.L.: Comparison of lidocaine, xylazine, and xylazine/lidocaine for caudal epidural analgesia in horses. J Am Vet Med Assoc 1992, 201, 1187-1190.
  • 8. Grubb T.L., Riebold T.W., Huber M.L.: Evaluation of lidocaine, xylazine, and a combination of lidocaine and xylazine for epidural analgesia in Ilamas. J Am Vet Med Assoc 1993, 203, 1441-1443.
  • 9. Grubb T.L., Riebold T.W., Crisman R.O.: Comparison of lidocaine, xylazine, and lidocaine-xylazine for caudal epidural analgesia in cattle. Vet Anaesth Analg 2002, 29, 64-68.
  • 10. Hall L.W., Clarke K.W., Trim C.M.: Veterinary Anesthesia, 10th ed., Philadelphia, Saunders Co., 2001, pp. 225-247.
  • 11. LeBlanc P.H., Caron J.P., Patterson J.S.: Epidural injection of xylazine for perineal analgesia in horses. J Am Vet Med Assoc 1989, 193, 1405-1408.
  • 12. LeBlanc P.H., Caron J.P.: Clinical use of epidural xylazine in the horse. Eq Vet J 1990, 23, 180-181.
  • 13. Mensink F.J., Kozody R., Kehloer C.H.: Dose response relationship of Clonidine in tetracaine spinal anesthesia. Anesthesiology 1987, 67, 717-721.
  • 14. Mohammed A., Liman M..: Xylazine (Chanazine®) as an epidural anaesthetic agent in sheep. Small Rum Res 1998, 27, 85-87.
  • 15. Nanda A.S., Nakao T.: Role of buffalo in the socioeconomic development of rural Asia: current status and future prospectus. Anim Sci J 2003, 74, 443-455.
  • 16. Nishikawa T., Dohi S.: Clinical evaluation of clonidine added to lidocaine solution for epidural anesthesia. Anesthesiology 1990, 73, 853-859.
  • 17. Nowrouzian I., Adib-Hashemi F.A., Ghamsari S.M.: Evaluation of epidural analgesia with xylazine HCL in cattle. Vet Med Rev 1991, 61, 13-17.
  • 18. Ralcle J.P., Benkhadra A., Poy J.P.: Prolongation of isobaric bupivacaine spinal anesthesia with epinephrine and clonidine for hip surgery in the elderly. Anesth Analg 1987, 66, 442-446.
  • 19. Singh H., Roy K.S.: Atlas of the Buffalo Anatomy, 1st ed., New Dehli, Vinayak Press, 1997, pp. 489-497.
  • 20. Singh V., Amarpal K.P., Aithal H.P.: Medetomidine with ketamine and bupivacaine for epidural analgesia in buffaloes. Vet Res Commun 2005, 29, 11-18.
  • 21. Tiwari S.K., Kumar A., Vainio O.: Reversal of sedative and clinicophysiological effects of epidural xylazine and detomidine with atipamezole and yohimbine in buffaloes (Bubalus bubalis). Vet Rec 1998, 143, 529-532.

Typ dokumentu

Bibliografia

Identyfikatory

Identyfikator YADDA

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