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2004 | 07 | 3 |

Tytuł artykułu

Modification of zearalenone structure in model and natural conditions

Warianty tytułu

Języki publikacji

EN

Abstrakty

EN
Zearalenone is a mycotoxin widely occurring in cereals and animal feed, and it is associated with hyperestrogenism and other reprodutive disorders in animals. A new method of detoxication of feed- stuffs involves alkaline hydrolysis of toxic macrolactone (1) (as well as model compounds (2a, 2b)). The method caused modification of zearalenone structure under mild conditions and the toxin underwent irreversible hydrolysis with high efficiency.

Wydawca

-

Rocznik

Tom

07

Numer

3

Opis fizyczny

p.181-185,fig.,ref.

Twórcy

autor
  • Jagiellonian University, Ingardena 3, 30-060 Krakow, Poland
autor
autor
autor
autor
autor

Bibliografia

  • Barton P, Laws AP, Page MI (1994) Structure-activity rela­tionship in the esterase-catalysed hydrolysis and transes­terification of esters and lactones. J Chem Soc Perkin Trans 2: 2021-2028.
  • Bata H, Lhsztity L (1999) Detoxification of mycotoxin-con- taminated food and feed by microorganisms. Trends Food Sci Technol 10: 223-228.
  • Berek L, Petri IB, Mesterhazy A, Teren J, Molnhr J (2001) Effects of mycotoxins on human immune functions in vitro. Toxicol in Vitro 15: 25-30.
  • Creppy EE (2001) Update of survey, regulation and toxic effects of mycotoxins in Europe. Toxicol Lett 127: 19-28.
  • D’Mello JPF, Placinta CM, and Macdonald AMC (1999) Fusarium mycotoxins: a review of global implications for animal health, welfare and productivity. Anim Feed Sci Tech 80: 183-205.
  • Doyle MP, Applebaum RS, Brackett RE, Marth EH (1982) Physical, chemical and biological degradation of- mycotoxins in foods and agricultural commodities. J Food Prot 45 : 946-971.
  • Fink-Gremmels J (1999) Mycotoxins: Their implications for human and animal health. Vet Q 21: 115-120.
  • Hussein HS, Brasel JM (2001) Toxicity, metabolism and im­pact of mycotoxins on humans and animals. Toxicology 167: 101-134.
  • Huwig A, Freymund S, Kappeli O, Dutler H (2001) My- cotoxin detoxication of animal feed by different adsor­bents. Toxicol Lett 122: 179-188.
  • Lin L, Zhang J, Wang P, Wang Y, Chen J (1998) Thin-layer chromatography of mycotoxins and comparison with other chromatographic methods. J Chromatogr A 815: 3-20.
  • Mali RS, Babu KN (1998) Reactions of 3-(l-hydroxyalkyl)phthalides with acids: synthesis of (Z)-3-alkylidenephthalides and 3-alkyI-8-hy-droxyisocoumarins. J Org Chem 63: 2488-2492.
  • Obremski K, Gaj^cki M, Zwierzchowski W, Bakula T, Apoznanski J, Wojciechowski J (2003) The level of zearalenone and h-zearalenol in the blood of gilts with clinical symptoms of toxicosis, fed diets with a low zearalenone content. J Anim Feed Sci 12: 529-538.
  • Onji Y, Aoki Y, Tani N, Umebayashi K, Kitada Y, Dohi Y (1998) Direct analysis of several Fusarium mycotoxins in cereals by capillary gas chromatography-mass spec­trometry. J Chromatogr A 815: 59-65.
  • Park DL (1993) Perspectives on mycotoxin decontamination procedures. Food Addit Contam 10: 49-60.
  • Placinta CM, D’Mello JPF, Macdonald AMC (1999) A re­view of worldwide contamination of cereal grains and ani­mal feed with Fusarium mycotoxins. Anim Feed Sci Tech 78: 21-37.
  • Shipchandler MT (1973) Chemistry of zearalenone and some of its derivatives. Heterocycles 3: 471-520.
  • Trenholm HL, Prelusky DB, Young JC and Miller JD (1988) A practical guide the prevention of fusarium mycotoxin in grain and animal feedstuffs. Arch Enviromn Contam Toxi­col 18: 443-451.
  • Urry WH, Wehrmeister HL, Hodge EB, Hidy PH (1966) The structure of zearalenone. Tetrahedron Lett 27: 3109-3114.
  • Visconti A, Pascale M (1998) Determination of zearalenone in corn by means of immunoaffinity clean-up and height-performance liquid chromatography with fluor­escence detection. J Chromatogr A 815: 133-140.

Typ dokumentu

Bibliografia

Identyfikatory

Identyfikator YADDA

bwmeta1.element.agro-article-bd7347e2-a311-4842-b222-cd28ad1fde9d
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