Dynamics of peripheral blood lymphocytes in rabbits experimentally infected with two Czech strains of RHD virus

• Autorzy: Hukowska-Szematowicz B , Deptula W.
• Języki publikacji: EN

Abstrakty

EN

Changes in the number of T and B lymphocytes and their subpopulations (Th, Tc/Ts, cells with CD25+ receptor) in peripheral blood of rabbits experimentally infected with one of two Czech strains (CAMPV-351 and CAMPV-561) of RHD virus were studied. The lymphocytes were identified using a cytometer and monoclonal antibodies directed against CD5+ (at T lymphocytes), CD4+ (at Th lymphocytes), CD8+ (at Tc/Ts lymphocytes), CD25, or IgM receptor at B lymphocytes. In addition, disease symptoms were recorded in the infected rabbits and their mortality was monitored. Analysis of the results showed that the examined strains induced a distinct immune response of the lymphocytes and that the response was more pronounced following the infection with the CAMPV-561 strain. The recorded changes were expressed more frequently by an increased than decreased percentages of the examined lymphocytes. The mortality was variable and reached 30% in animals infected with the CAMPV-351 strain and 75% in animals infected with the CAMPV-561 strain.

Słowa kluczowe

EN

viral disease; rabbit; Caliciviridae; disease symptom; RHD virus; veterinary medicine; rabbit hemorrhagic disease; B lymphocyte; peripheral blood; animal disease; mortality; T lymphocyte

• Wydawca: -
• Czasopismo: Bulletin of the Veterinary Institute in Puławy
• Rocznik: 2008
• Tom: 52
• Numer: 1
• Opis fizyczny: p.23-29,ref.

Twórcy

autor

Hukowska-Szematowicz B

• University of Szczecin, 71-412 Szczecin, Poland

autor

Deptula W.

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