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2006 | 62 | 09 |

Tytuł artykułu

Ekspresja receptorow estrogenowych alfa w zakrecie przyhipokampowym samic krolikow po 17beta estradiolu

Warianty tytułu

EN
Expression of estrogen receptors alpha in parahippocampal gyrus following 17beta estradiol application in female rabbits

Języki publikacji

PL

Abstrakty

EN
The aim of the study was to determine the localization of estrogen receptors α in the parahippocampal gyrus (gyrus parahippocampalis) following 17β application in ovariectomized rabbits. Studies were carried out using an immunocytochemical method. Estrogen receptors a immunoreactivity in neurons and astrocytes were detected in the cellular layers of parasubiculum, perisubiculum and entorhinalis region. However ERα immunoreactivity was not detected in astrocytes ovariectomized rabbits in the experimental group where there was no E2 application. On the other hand, the neurons showed very weak colorization. The results obtained indicate that the structure of rabbit parahippocampal gyrus is under the influence of estrogen, which causes an increase in ERα expression.

Wydawca

-

Rocznik

Tom

62

Numer

09

Opis fizyczny

s.1059-1060,rys.,bibliogr.

Twórcy

autor
  • Akademia Rolnicza, ul.Akademicka 12, 20-033 Lublin

Bibliografia

  • 1.Caba M., Beyer C., Gonzáles-Mariscal G., Morrell J. I.: Immunocytochemical detection of estrogen receptor-α in the female rabbit forebrain: topography and regulation by estradiol. Cell Neuroendocrinol. 2003, 77, 208-222.
  • 2.Caldwell J. D.: A sexual arousability model involving steroid effects at the plasma membrane. Neurosci. Behav. Rev. 2002, 26, 13-30.
  • 3.Dhanadapani K. M., Brann D. W.: Estrogen-astrocyte interactions: implications for neuroprotection. BMC Neurosci. 2002, 3, 6.
  • 4.Donahue J. E., Stopa E. G., Chorsky R. L., King J. C., Schipper H. M., Tobet S. A., Blaustein J. D., Reichlin S.: Cells containing immunoreactive estrogen receptor-α in the human basal forebrain. Brain Res. 2000, 856, 142-151.
  • 5.Garcia-Segura L. M., Chowen J. A., Dueñas M., Torres-Aleman I., Naftalin F.: Gonadal steroids as promoters of neuro-glial plasticity. Psychoneuroendocrinol. 1994, 19, 445-453.
  • 6.Hősli E., Rűhl W., Hősli L.: Histochemical and electrophysiological evidence for estrogen receptors on cultured astrocytes: colocalization with cholinergic receptors. Int. J. Devl. Neurosci. 2000, 18, 101-111.
  • 7.Jaworska-Adamu J., Cybulska R., Kalinowska M.: Zmiany morfologii astrocytów w istocie szarej środkowej i jądrze łukowatym w cyklu rujowym szczura. Medycyna Wet. 2004, 60, 1114-1117.
  • 8.Langub M. C., Watson R. E.: Estrogen receptor-immunoreactive glia, endothelia and ependyma in guinea pig preoptic area and median eminence: electron microscopy. Endocrinology 1992, 130, 364-372.
  • 9.Luquin S., Naftolin F., Garcia-Segura L. M.: Natural fluctuation and gonadal hormone regulation of astrocytes immunoreactivity in dentate gyrus. J. Neurobiol. 1993, 24, 913-924.
  • 10.Milner T. A., McEwen B. S., Hayashi S., Li C. J., Reagan L. P., Alves S. E.: Ultrastructural evidence that hippocampal alpha receptors are located at extranuclear sites. J. Comp. Neurol. 2001, 429, 355-371.
  • 11.Mitra S. W., Hoskin E., Yudkovitz J., Pear L., Wilkinson H. A., Hayashi S., Pfaff D. W., Ogawa S., Rohrer S. P., Schaeffer J. M., McEwen B. S., Alves S. E.: Immunolocalization of estrogen receptor β in the mouse brain comparison with estrogen receptor α. Endocrinol. 2003, 144, 2055-2067.
  • 12.Oswald S.: Topographic organization of the projections from the entorhinal area to the hippocampal formation of the rat. J. Comp. Neurol. 1986, 167, 285-314.
  • 13.Rune G. M., Wehrenberg U., Prange-Kiel J., Zhou L., Adelmann G., Frotscher M.: Estrogen up-regulates estrogen receptor α and synaptophysin in slice cultures of rat hippocampus. Neurosci. 2002, 113, 167-172.
  • 14.Szczech J.: Mielinizacja układu limbicznego w rozwoju ontogenetycznym szczura. Neuropatol. Pol. 1978, 16, 25.

Typ dokumentu

Bibliografia

Identyfikatory

Identyfikator YADDA

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