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2010 | 19 | 2 |

Tytuł artykułu

Evaluation of methods used in vivo to estimate the transfer of amino acids and other substrates into the cells of mammary gland

Warianty tytułu

Języki publikacji

EN

Abstrakty

EN
In recent years some approaches were developed to estimate the parameters of transport of amino acids and other substrates into the cell in vivo using arteriovenous concentration difference and volume blood flow data with their recalculation according to kinetic model of the system: capillary - interstitium - cell. With the use of literature data and the own results the authors analysed the present feasibility of this method in the studies of mammary metabolism in productive ruminants The model estimates were compared with independent measurements (with 13С-amino acids), the verifying experiments were conducted and some unresolved problems and errors of interpretation were investigated. The method is recommended to study the adaptive shifts in the activity of amino acid transport into the mammary secretory cells during milk formation in various nutritional states.

Wydawca

-

Rocznik

Tom

19

Numer

2

Opis fizyczny

p.183-194,fig.,ref.

Twórcy

  • Russian Academy of Agricultural Sciences, Borovsk-3, Kaluga Region, 249013, Russia
autor

Bibliografia

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  • Baumrucker C.R., 1985. Amino acid transport systems in bovine mammary tissue. J. Dairy Sci. 68, 2346-2451
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  • Cherepanov G.G., Tokarev T.Y., Makar Z.N., 2003. Indirect determination of activity of metabolite transport into the cell in vivo using measurement of arteriovenous balance of the metabolite. Russ. J. Physiol. 89, 1021-1028
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  • Crawhall J.C., Purkiss P., 1973. Transport of methionine and proline by rat liver slices and the effect of certain hormone. Biochem. J. 136, 15-24
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  • Hanigan M.D., France J., Wray-Cahen D., Beever D.E., Lobley G.E., Reutzel L., 1998a. Alternative models for analyses of liver and mammary transorgan metabolite extraction data. Brit. J. Nutr. 79, 63-78
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  • Makar Z.N., Cherepanov G.G., Boyarshinov I.A., Korneeva R.I., Matyushenko P.V., 2003. Relationship between organ blood supply, uptake of substrates by the mammary gland, activity of their transport into the cells and byosynthesis of milk components in dairy cows. Russ. J. Physiol. 89, 951-959
  • Makar Z.N., Cherepanov G.G., Sapunov M.I., Korneeva R.I., 2007. Lactogenic effects of hyperinsulinemic-euglycemic clamp in goats. Russ. J. Physiol. 93, 402-411
  • Neville M.C., Hay W.W., Fennessy P., 1990. Physiological significance of the concentration of human milk glucose. Protoplasma 159, 118-128
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  • Trottier N.L., Shipley C.F., Easter R.A., 1997. Plasma amino acid uptake by the mammary gland of the lactating sows. J. Anim. Sci. 75, 1266-1278 of certain hormone. Biochem. J. 136, 15-24

Typ dokumentu

Bibliografia

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