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2005 | 54 | 4 |

Tytuł artykułu

The action of photosensitizers and serum in a bactericidal process. II. The effects of dyes: hypericin, eosin Y and saphranine O

Warianty tytułu

Języki publikacji

EN

Abstrakty

EN
The aim of the present work was to recognize the reasons for differences in the photodynamic action of dyes against various bacterial strains. It is expected that a better understanding of this problem may help in design of new photosen-sitizers. The sensitivity of 6 various bacterial strains to the photodynamic action of 5 photosensitizers was determined. The hydrophobicity of cell surface and susceptibility of bacteria to the natural defense mechanism of human serum, were estimated. The differences in the photodynamic efficiency of dyes could be contributed to various affinities of cell membrane to dyes, to known details of membrane architecture as well as to different mechanisms of photosensitization.

Wydawca

-

Rocznik

Tom

54

Numer

4

Opis fizyczny

p.323-330,fig.,ref.

Twórcy

autor
  • University of Zielona Gora, Monte Cassino 21 b, 65-561 Zielona Gora, Poland
autor
autor
autor

Bibliografia

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  • Castael M., A. Gold, L. Ball and M. Sobsey. 2003. Photosensitization of hepatitis A virus (HAV) and other microbes by meso substituted porphyrins in water. Proceedings, Water Quality Technology Conference, p. 76-89.
  • Doiron D. and Ch. Gomer. 1984. Porphyrin Localization and Treatment of Tumors. A.R. Riss, N.York.
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  • Gabor R, K. Szocs, P. Maillard, G. Csik. 2001. Photobiological activity of cells, exogenous and endogenous porphyrin derivatives in Escherichia coli and Enterococcus hirae. Radiation and environmental biophysics. 40: 145-151.
  • Halliwell B. and M. Gulleridge. 1989. Free Radicals in Biology and Medicine. 2 Ed. Oxford Univ. Press. Oxford.
  • Halliwell B. and M. Gutteridge. 1990. Role of free radicals and catalytic metal ions in human diseases. An overview. Methods Enzym. 186: 1-85
  • Haugland R. 1996. Handbook of Fluorescent Probes and Research Chemicals (6th ed). Molecular Probes. Eugene, USA.
  • Jankowski A., S. Jankowski and A. Mirończyk. 2003. Synergistic action of photosensitizers and of normal human serum in a bactericidal process. I. Effect of chlorophylls. Acta Microbiol. Polon. 52: 373-378.
  • Jankowski S. 1995. Defense mechanisms protecting Gram negative bacteria against the bactericidal action of complement (in Polish). Post. Mikrobiol. 37: 23-44.
  • Jankowski S., J. Sarowska, H. Żarczyńska and A. Cisowska. 1997. Hydrophobic properties of Pseudomonas strains (in Polish). Med. Dosw. Mikrobiol. 49: 187-190.
  • Joiner K. 1988. Complement evasion by bacteria and parasites. Ann. Rev. Microbiol. 42: 201-209.
  • Jori G. and C. Preria. 1985. Photodynamic Therapy of Tumors and other Diseases. Libreria Progetto, Padova.
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  • Wilson M. 2004. Lethal photosensitization of oral bacteria and its potential application in the photodynamic therapy of oral infections. Photochem. Photobiol. Sci. 3: 412-418.

Typ dokumentu

Bibliografia

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