Characterization of Bacillus subtilis clones surviving overproduction of Zeta, a pSM19035 plasmid-encoded toxin

• Autorzy: Nowakowska B. , Kern-Zdanowicz I. , Zielenkiewicz U. , Ceglowski P.
• Języki publikacji: EN

Abstrakty

EN

The postsegregational killing system of pSM19035 plasmid consists of the proteins Zeta and Epsilon, a toxin and an antidote, respectively. Zeta mutants were isolated with the use of Bacillus subtilis strain with the zeta gene under control of an inducible promoter integrated into the chromosome. Results of mutant analysis point to the amino terminal part of the Zeta protein as being responsible for the toxicity.

Słowa kluczowe

EN

Zeta mutant; Zeta protein; Epsilon protein; Gram-positive bacterium; postsegregational killing system; clone; Bacillus subtilis; toxin; plasmid stable maintenance

• Wydawca: -
• Czasopismo: Acta Biochimica Polonica
• Rocznik: 2005
• Tom: 52
• Numer: 1
• Opis fizyczny: p.99-107,fig.,ref.

Twórcy

autor

Nowakowska B.

• Polish Academy of Sciences, A.Pawinskiego 5A, 02-106 Warsaw, Poland

autor

Kern-Zdanowicz I.

autor

Zielenkiewicz U.

autor

Ceglowski P.

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