The distribution and chemical coding of neurons in the celiac-superior mesenteric ganglion complex supplying the normal and inflamed ileum in the pig

• Autorzy: Kaleczyc J. , Pidsudko Z. , Franke-Radowiecka A. , Sienkiewicz W. , Majewski M. , Lakomy M. , Timmermans J.P.
• Języki publikacji: EN

Abstrakty

EN

The present study investigated the chemical coding of neurons in the celiac-superior mesenteric ganglion complex supplying the normal (n = 4) and inflamed (n=4) ileum (chemically-in- duced inflammation) in juvenile pigs using retrograde tracing combined with immunohistochem- istry. Ileum-projecting neurons (IPN) were predominantly distributed in the left and right superior mesenteric pools of the ganglion. The majority of them were adrenergic (tyrosine hydroxylase-positive) and also contained neuropeptide Y, somatostatin or galanin. No clear-cut differences in the distribution and chemical coding of IPN were found between normal and inflamed pigs. However, in the inflamed group, the density of peptidergic, IPN-associated nerve fibres was higher than that found in the control group.

Słowa kluczowe

EN

celiac-superior mesenteric ganglion; pig; inflammation; neuron; biologically active substance; distribution; ileum; chemical coding

• Wydawca: -
• Czasopismo: Polish Journal of Veterinary Sciences
• Rocznik: 2004
• Tom: 07
• Numer: 3
• Opis fizyczny: p.199-201,fig.,ref.

Twórcy

autor

Kaleczyc J.

• University of Warmia and Mazury in Olsztyn, Oczapowskiego 13, 10-719 Olsztyn, Poland

autor

Pidsudko Z.

autor

Franke-Radowiecka A.

autor

Sienkiewicz W.

autor

Majewski M.

autor

Lakomy M.

autor

Timmermans J.P.

Bibliografia

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• Majewski M (2000) Synaptogenesis and structure of the au­tonomic ganglia. Folia Morphol (Warsz) 58:65-99
• Sharkey KA, Kroese AB (2001) Consequences of intestinal inflammation on the enteric nervous system: neuronal ac­tivation induced by inflammatory mediators. Anat Rec 262: 79-90.
• Trudrung P, Furness JB, Pompolo S, Messenger JP (1994) Locations and chemistries of sympathetic nerve cells that project to the gastrointestinal tract and spleen. Arch His- tol Cytol 57: 139-150.