Elimination dynamics of nickel, administered by a single intraperitoneal injection, in common carp, Cyprinus carpio L.

• Autorzy: Brucka-Jastrzebska E , Protasowicki M.
• Języki publikacji: EN

Abstrakty

EN

Background. Some heavy metals are essential to living organisms but their excess can disturb the homeostasis of an animal. The aim of the study was to assess effects of nickel compounds on carp, Cyprinus carpio L., and to follow the toxicodynamics of this metal elimination from intoxicated fish once they were transferred to a clean ambience. Materials and Methods. Individuals of carp, Cyprinus carpio L. were given a single intraperitoneal injection of a sub-lethal nickel nitrate dose (60 μg Ni ּkg-1 body weight) to assess their detoxification potential following transfer to uncontaminated habitat. The 60-day experiment was divided into 8 stages during which various organs and tissues of the fish (liver, kidneys, skin, gills, alimentary tract, muscles) were examined and subjected to assays for nickel contents at pre-set times. Nickel was determined with inductively coupling plasma atomic emission spectrometry (ICP-AES) in a JY-24 Jobin Yvon apparatus after wet digestion in concentrated HNO3 in CEM MDS 2000 microwave oven. Results. The fish intoxicated with Ni shown some behavioural changes; they were sluggish and stay near the bottom of a tank, their responses to light and sound were much slower than those of the control fish. The nickel level was observed to change with time: after initial nickel accumulation in the tissues, the metal was eliminated. The experiment highlighted changes in the intoxicated carp system during the process of detoxification. The highest biological half-life (t1/2) of nickel was recorded in alimentary tract (10 days), the lowest being typical of the liver (1.8 days). Conclusion. During detoxification, nickel was observed to be redistributed among the examined organs. Its elimination rate was depended on organ and varied from 0.003 to 0.008 µgּday-1. A long-term effect of sub-lethal intoxication was an about 5 % reduction of the fish body weight. This study has been financially supported by the State Committee for Scientific Research (KBN) (grant No. 3 PO4E 030 22).

Słowa kluczowe

EN

carp; fish; Cyprinus carpio; intoxication; common carp; elimination; dynamics; nickel

• Wydawca: -
• Czasopismo: Acta Ichthyologica et Piscatoria
• Rocznik: 2004
• Tom: 34
• Numer: 2
• Opis fizyczny: p.181-192,fig.,ref.

Twórcy

autor

Brucka-Jastrzebska E

• University of Szczecin, al.Piastow 40b, 71-065 Szczecin, Poland

autor

Protasowicki M.

Bibliografia

• Anonymous, 1991. Rozporządzenie Ministerstwo Ochrony Środowiska Zasobów Naturalnych i Leśnictwa z dn. 5.11.1991 r. w sprawie klasyfikacji wód oraz warunków, jakim powinny odpowiadać ścieki wprowadzane do wód lub ziemi. [Directive of the Minister of Environmental Protection, Natural Resources, and Forestry of 5 November 1991 on water classification and standards for sewage discharged to waters and soils.] 116 (503):1579–1583. (In Polish.)
• Grabowski T., 2003. Farmakokinetyka i biofarmacja. [Pharmacokinetics and biopharmacy.] http://www.biokinetica.pl/farmakokinetyka.pdf (In Polish.)
• Heath A.G., 1990. Water pollution and fish physiology. CRC Press, Boca Raton.
• Hellou J., Warren W.G., Payne J.F., Belkhode S., Lobel P., 1992. Heavy metals and Rother elements in three tissues of cod, Gadus morhua from the Northwest Atlantic. Marine Pollution Bulletin 24 (9): 452–458.
• Hirt A. R., Teinfalt M., Dederichs D., van den Hoven R., 2003. The effect of orally administered merbofloxacin on the pharmacokinetics of theophylline. Journal of Veterinary Medicine A 50 (5): 246–256.
• Kołacz R., Dobrzański Z., Bodak E., 1996. Bioakumulacja Cd, Pb i Hg w tkankach zwierząt.[Bioaccumulation of Cd, Pb, and Hg in animal tissues.] Medycyna Weterynaryjna 52 (11):686–692. (In Polish.)
• Murray R. K., Granner D. K., Mayes P. A., Rodwell V. W., 1999. Biochemia Harpera [Harper’s biochemisty.] PWZL, Warszawa. (In Polish.)
• Pawelski S., Maj S., 1987. Normy i kliniczna interpretacja badań diagnostycznych w medycynie wewnętrznej. [Standards and clinical interpretation of diagnostic analyses In internal medicine.] PZWL, Warszawa. (In Polish.)
• Prost M., 1994. Choroby ryb. [Fish diseases.] PTNW, Lublin. (In Polish.)
• Protasowicki M., 1991. Long-term studies on heavy metals in aquatic organisms from the river Odra mouth area. Acta Ichthyologica et Piscatoria 21 (Suppl.): 301–309.
• Protasowicki M., Chodyniecki A. 1992. Bioaccumulation of cadmium in some organs of carp, Cyprinus carpio L., in case of per os administration. Archives of Polish Fisheries 1: 61-66.
• Ray D., Banerjee K., Chatterjee M., 1990. Bioaccumulation of nickel and vanadium In tissues of the catfish Clarias batrachus. Journal of Inorganic Biochemistry 38: 169–173.
• Rice D.W., Harrison F.L., 1978. Copper sensitivity of pacific herring, Clupea harengus pallasi, during its early life history. Fishery Bulletin 76 (2): 347–356.
• Sharif A.K.M., Mustafa A.I., Amin M.N., Safiullah S., 1991. Trace element concentrations in tropical marine fish from the Bay of Bengal. Science of the Total Environment 138:223–234.
• Sobecka E., 1998. Wpływ niklu na organizm suma europejskiego Silurus glanis L. [Nikel effects on the European wells, Silurus glanis L.] PhD Thesis, Agricultural University of Szczecin, Poland. (In Polish.)
• Sobecka E., 2001. Changes in the iron level in the organs and tissues of wells catfish, (Silurus glanis L.) caused by nickel. Acta Ichthyologica et Piscatoria 31 (2): 127–143.
• Sreedevi P., Sivaramakrishna B., Suresh A., Radhakrishnaiah K., 1992. Effect of Nikel on some aspects of protein metabolism in the gill and kidney of the freshwater fish,Cyprinus carpio L. Environment Pollutions 77: 59–63.
• Svobodova Z., Groch L., Flajshans M., Vykusova B., Machova J., 1997. The effect of longterm therapeutic bath of malachite green on common carp (Cyprinus carpio L.). Acta Veterinaria Brno 66: 111–117.
• Windom H., Stein D., Sheldon R., Smith R. Jr., 1987. Comparison of trace metal concentrations in muscle tissue of a benthopelagic fish (Coryphaenoides armatus) from the Atlantic and Pacific oceans. Deep-Sea Research 34 (2): 213–220.
• Żmudzki J., Szkoda J., 1996. Narażenie człowieka na pierwiastki toksyczne. Metale i metaloidy – aspekty farmakologiczne, toksykologiczne i Erodowiskowe. [Human exposure to toxic elements. Metals and metalloids—pharmacological, toxicological, and environmental aspects.] Oficyna Wydawnicza Akademii Medycznej w Białymstoku, Białystok No. 220. (In Polish.)