Prenatalna ontogeneza limfocytow u swin

• Autorzy: Pomorska-Mol M , Markowska-Daniel I.

Warianty tytułu

EN

Prenatal ontogeny of lymphocytes in pigs

• Języki publikacji: PL

Abstrakty

EN

The structure and function of the immune system of pigs are the main subjects of interest to numerous research centers, which is undoubtedly related to the potential of using pig organs in xenotransplantation. Another reason for intensive studies on this subject is the need for secure and effective immunoprophylaxis of pigs and the improvement of their immunological status. The present paper presents the current knowledge on the prenatal ontogeny of lymphocytes in pigs. The ontogeny of pigs’ immune system starts in early gestation. During the prenatal period the system undergoes numerous changes which ultimately result in its achievement of immunological competence. Although the immune system in pigs is physiologically developed already on the 35th day of pregnancy, only a small numbers of lymphocytes and other lymphatic elements can be detected in fetal organs. The hematopoiesis in bone morrow starts around the 45th day of pregnancy. Lymph nodes, including mesenteric lymph nodes, are devoid of their defense function until the 70th day of prenatal life. The most dynamic development of the immune system of pigs takes place between the 60th and 90th day of gestation. To a greater extent, the diffusion of lymphocytes in secondary lymphatic organs occurs after birth, and the intensity of this process seems to be related to the colonization of the gut and enhanced by the contact of newborns with environmental antigens.

Słowa kluczowe

PL

trzoda chlewna; uklad odpornosciowy; rozwoj prenatalny; ontogeneza; limfocyty T; limfocyty B; komorki NK

• Wydawca: -
• Czasopismo: Medycyna Weterynaryjna
• Rocznik: 2010
• Tom: 66
• Numer: 01
• Opis fizyczny: s.17-21,tab.,bibliogr.

Twórcy

autor

Pomorska-Mol M

• Panstwowy Instytut Weterynaryjny - Panstwowy Instytut Badawczy, Al.Partyzantow 57, 24-100 Pulawy

autor

Markowska-Daniel I.

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