The influence of inflammation on the expression of neuropeptides in the ileum-projecting primary sensory neurones in the pig

• Autorzy: Pidsudko Z , Wasowicz K. , Sienkiewicz W. , Kaleczyc J. , Czaja K. , Lakomy M.
• Języki publikacji: EN

Abstrakty

EN

In the present study the ELISA test was used to investigate the influence of chemically-induced ileitis on the dorsal root ganglia (DRG) neurons in the pig. The preliminary retrograde fluorescent tracing study revealed that ileum-projecting sensory neurones (IPN) are located in the thoracic ganglia (Th; Th₈–Th₁₃). The ileum wall in experimental (E) pigs was subjected to multiple injection with 4% paraformaldehyde to induce inflammation, while in the control (C) animals the organ was injected with 0.1 M phosphate buffer. Three days later the DRGs (Th₈–Th₁₃) collected from all the animals were evaluated for VIP, SP, CGRP, NPY, GAL and SOM content with an ELISA test. It was found that the inflammation increased clearly the tissue level of SP, GAL and SOM.

Słowa kluczowe

EN

inflammation; expression; neuropeptide; ileum; primary sensory neuron; pig; ELISA test; dorsal root ganglion

• Wydawca: -
• Czasopismo: Folia Morphologica
• Rocznik: 2003
• Tom: 62
• Numer: 3
• Opis fizyczny: p.235-237,fig.,ref.

Twórcy

autor

Pidsudko Z

• Warmia and Mazury University in Olsztyn, Oczapowskiego 13, 10-719 Olsztyn, Poland

autor

Wasowicz K.

autor

Sienkiewicz W.

autor

Kaleczyc J.

autor

Czaja K.

autor

Lakomy M.

Bibliografia

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