EN
The first clinical cases of proliferative ileitis were recognized in two large pig farms in the western part of Poland in 1995. Both farms were well managed and had a high hygienic status. A reproductive herd in farm P consisted of approx. 350 sows and in newly established farm S of 170 gilts and 20 boars. The clinical picture of the disease was observed in about 10 per cent of weaned and fattening pigs in farm P and in about 20 per cent of the gilts and boars in farm S. The most pathogenic clinical sign was chronic diarrhoea of grey-brown faeces. The diseased animals exhibited a very poor performance. Mortality of the affected pigs reached 2 per cent. Gross lesions of the ileum and other parts of the small intestine were covered by a characteristic reticulated serous exudate. Histopathologically, diffusive microscopic lesions with proliferative enteropathy were observed. Affected crypts were enlarged and branched. Excellent theraupetic results were obtained by the treatment of all pigs with 100 ppm of tiamulin in farm S and with 100 ppm of tylosine in farm P.