Misoprostol as agonist of IP2 receptor

• Autorzy: Goszcz A. , Bieron K. , Grodzinska I.
• Języki publikacji: EN

Abstrakty

EN

Fourteen patients with peripheral vascular disease received 200 µg of misoprostol 3 times a day during one month. The therapy with misoprostol caused clinical and biochemical improvement in all 14 patients. An elongation of pain free and maximum walking distance, shortening of pain duration and increase in arterial blood flow in both calves were observed. At the same time an activation of the fibrinolytic system, rise in the platelet aggregate ratio and increase in cAMP levels were noticed. It is suggested that misoprostol in human being caused rather activation of IP2 receptor.

Słowa kluczowe

EN

arterial blood flow; peripheral vascular disease; IP2 receptor; misoprostol

• Wydawca: -
• Czasopismo: Journal of Physiology and Pharmacology
• Rocznik: 2002
• Tom: 53
• Numer: 4,1
• Opis fizyczny: p.635-641,fig.

Twórcy

autor

Goszcz A.

• Jagiellonian University Medical College, 31-531 Krakow, Poland

autor

Bieron K.

autor

Grodzinska I.